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https://www.sciencedirect.com/science/article/pii/S0169409X01001107
Cationic lipid–DNA complexes in gene delivery: from biophysics to biological applications. ... Despite the extensive use of cationic liposomes for gene delivery in vitro and in vivo, the mechanisms by which they deliver DNA into cells are not well understood. ... D.D LasicRecent developments in medical applications of …Author: Maria C Pedroso de Lima, Sérgio Simões, Pedro Pires, Henrique Faneca, Nejat Düzgüneş
https://www.researchgate.net/publication/7471375_Cationic_liposomes_for_gene_delivery
Cationic liposomes for gene delivery. ... examples illustrating the potential of cationic liposomes in clinical applications will be provided. ... ing the biological activity of lipoplexes and o ...
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=0929-8673&volume=10&issue=14&spage=1221
Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications. ... have prompted investigators to develop alternative methods for gene delivery, cationic lipid-based systems being the most representative. Despite extensive research in the last decade on the use of cationic liposomes as gene transfer vectors and the ...
https://www.researchgate.net/profile/Henrique_Faneca/publication/7471375_Cationic_liposomes_for_gene_delivery/links/549560650cf29b944823add3.pdf
Cationic liposomes for gene delivery 4 Expert Opin. Drug Deliv. (2005) 2(2) can limit their application, as the stability of lipoplexes on stor-age or in biological fluids can be drastically affected.
https://www.ingentaconnect.com/content/ben/cmc/2003/00000010/00000014/art00005
Cationic Liposomes for Gene Delivery: From Biophysics to Biological Applications Buy Article: $68.00 + tax ... Despite extensive research in the last decade on the use of cationic liposomes as gene transfer vectors and the development of elegant strategies to enhance their biological activity, these systems are still far from being viable ...
https://onlinelibrary.wiley.com/doi/10.1002/%28SICI%291521-3773%2819980803%2937%3A13/14%3C1768%3A%3AAID-ANIE1768%3E3.0.CO%3B2-4
Cationic liposomes are able to deliver nucleic acids to cells and are projected to be core technology for the emerging discipline of gene therapy. ... , Cationic liposome–DNA complexes: from liquid crystal science to gene delivery applications, Philosophical Transactions of the Royal Society A ... , Archives of Biochemistry and Biophysics, ...Author: Andrew D. Miller
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · These characteristics have led to applications in chemical and biochemical analytics, cosmetics, food technologies, and drug and gene delivery [7, 8]. There are numerous lipid formulations for each of these applications. However, this review will focus primarily on …Author: Daniel A. Balazs, Wt. Godbey
https://www.sciencedirect.com/science/article/pii/S181808761300010X
For example, Arg-Gly-Asp (RGD) peptide-modified liposomes were studied for their ability to enhance the delivery of nucleic acids to integrin receptor-expressing cells .RGD-modified cationic liposomes loaded with p-glycoprotein-specific siRNAs showed higher delivery to integrin receptor-expressing human breast cancer MCF7/A cells, resulting in significant silencing of p-glycoprotein.Author: Gayong Shim, Mi-Gyeong Kim, Joo Yeon Park, Yu-Kyoung Oh
https://en.wikipedia.org/wiki/Cationic_liposome
Cationic liposomes are structures that are made of positively charged lipids and are increasingly being researched for use in gene therapy due to their favorable interactions with negatively charged DNA and cell membranes. Upon interacting with negatively charged DNA, cationic liposomes form clusters of aggregated vesicles. At a critical density the DNA is condensed and becomes encapsulated ...
https://www.hindawi.com/journals/jdd/2011/326497/
There are numerous lipid formulations for each of these applications. However, this review will focus primarily on the use of liposomes for gene delivery. 2. Characteristics. Liposomes are generally formed by the self-assembly of dissolved lipid molecules, each of which contains a hydrophilic head group and hydrophobic tails.Author: Daniel A. Balazs, Wt. Godbey
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