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https://www.sciencedirect.com/science/article/pii/S0168365909002259
The use of block copolymer micelles (BCMs) for the targeted delivery of chemotherapeutics has proven to be a promising approach for improving the therapeutic efficacy of pharmaceutical cancer therapy.Author: Andrew S. Mikhail, Christine Allen
https://www.researchgate.net/publication/329121262_Block_Copolymer_Micelles_in_Drug_Delivery_and_Cancer_Therapy
Block copolymer micelles has been emerged as a better and safer alternatives to small surfactant molecules for drug delivery applications. This review is focused on the design of block copolymers ...
https://www.sciencedirect.com/science/article/pii/S0169409X14002099
The application of block copolymer micelles (BCMs) in oncology has benefitted from advances in polymer chemistry, drug formulation and delivery as well as in vitro and in vivo biological models. While great strides have been made in each of these individual areas, there remains some disappointment overall, citing, in particular, the absence of more BCM formulations in clinical evaluation and ...Author: Sina Eetezadi, Sandra N. Ekdawi, Christine Allen, Christine Allen
http://pubs.acs.org/doi/abs/10.1021/acs.molpharmaceut.7b00188
With countless preclinical studies on block copolymer micelles (BCMs) successfully demonstrating the superiority of these advanced drug delivery formulations over conventional formulations, it remains somehow discouraging that only a few have reached clinical evaluation and practice. With a critical eye, this review aims to compare and summarize the preclinical and clinical data available on ...Author: Loujin Houdaihed, James C. Evans, Christine Allen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6071246/
Jul 20, 2018 · Micelles as colloidal suspension have attracted considerable attention due to their potential use for both cancer diagnosis and therapy. These structures have proven their ability to deliver poorly water-soluble anticancer drugs, improve drug stability, and have good penetration and site-specificity, leading to enhance therapeutic efficacy.Author: Nemany A. N. Hanafy, Maged El-Kemary, Stefano Leporatti
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.7b00188
With countless preclinical studies on block copolymer micelles (BCMs) successfully demonstrating the superiority of these advanced drug delivery formulations over conventional formulations, it remains somehow discouraging that only a few have reached clinical evaluation and practice. With a critical eye, this review aims to compare and summarize the preclinical and clinical data available on ...Author: Loujin Houdaihed, James C. Evans, Christine Allen
https://www.ncbi.nlm.nih.gov/pubmed/28481116
Aug 07, 2017 · Overcoming the Road Blocks: Advancement of Block Copolymer Micelles for Cancer Therapy in the Clinic. Houdaihed L(1), Evans JC(1), Allen C(1). Author information: (1)Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto , Toronto, Ontario, Canada M5S 3M2.Author: Loujin Houdaihed, James C. Evans, Christine Allen
http://www.eurekaselect.com/157428/article
Title:Recent Progress of Crosslinking Strategies for Polymeric Micelles with Enhanced Drug Delivery in Cancer Therapy VOLUME: 26 ISSUE: 13 Author(s):Wei Fan, Luye Zhang, Yiwen Li and Haoxing Wu* Affiliation:Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Huaxi MR Research Center (HMRRC), …Author: Wei Fan, Luye Zhang, Yiwen Li, Haoxing Wu
http://onlinelibrary.wiley.com/doi/10.1002/adma.200700866/full
Jan 30, 2008 · DNA Block Copolymer Micelles – A Combinatorial Tool for Cancer Nanotechnology ... Preparation and self-assembly of a dual-functional copolymer for cancer therapy, Reactive and Functional Polymers, 73, 1, (89), (2013). Crossref.
https://link.springer.com/article/10.1007/s11095-010-0233-4
Aug 20, 2010 · Micelles are colloidal particles with a size around 5–100 nm which are currently under investigation as carriers for hydrophobic drugs in anticancer therapy. Currently, five micellar formulations for anticancer therapy are under clinical evaluation, of which Genexol-PM has been FDA approved for use in patients with breast cancer. Micelle-based drug delivery, however, can be improved in ...Author: Chris Oerlemans, Wouter Bult, Mariska Bos, Gert Storm, J. Frank W. Nijsen, Wim E. Hennink
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