We have collected information about Block Copolymer Micelles As A Solution For Drug Delivery Problems for you. Follow the links to find out details on Block Copolymer Micelles As A Solution For Drug Delivery Problems.
https://www.tandfonline.com/doi/abs/10.1517/13543776.15.1.63
Micelles, nanosized colloidal particles with a hydrophobic core and hydrophilic shell, can be successfully used for the solubilisation of various poorly soluble pharmaceuticals, and demonstrate a series of attractive properties as drug carriers. Polymeric micelles, such as micelles formed by amphiphilic block copolymers, are of a special interest as they possess high stability both invitro …Author: Vladimir P Torchilin
https://www.researchgate.net/publication/232051842_Block_copolymer_micelles_as_a_solution_for_drug_delivery_problems
Download Citation Block copolymer micelles as a solution for drug delivery problems Micelles, nanosized colloidal particles with a hydrophobic core and hydrophilic shell, can be successfully ...
https://www.sciencedirect.com/science/article/pii/S0169409X00001241
Block copolymer micelles hold promise for the delivery of drugs and genes. The most relevant feature of block copolymer micelles for this purpose is their formation of distinguished core–shell architecture.Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://www.sciencedirect.com/science/article/pii/S0168365905004906
Beyond solubilizing hydrophobic drugs, block copolymer micelles can also target their payload to specific tissues through either passive or active means. Prolonged in vivo circulation times and adequate retention of the drug within the carrier are prerequisites to successful drug targeting.Author: Geneviève Gaucher, Marie-Hélène Dufresne, Vinayak P. Sant, Ning Kang, Dusica Maysinger, Jean-Christo...
https://www.rug.nl/research/zernike/education/topmasternanoscience/ns190solmaz.pdf
Amphiphilic block copolymer micelles have been the focus of research for the last decades because of the promising properties as nano size drug delivery vehicles. In polar aqueous milieu, copolymers self assemble into micelle structures which consist of hydrophilic corona and hydrophobic core regions.
https://www.mdpi.com/2073-4360/12/4/869/htm
The word cloud of 2009 also shows the growing concerns about the behavior of block copolymers in solution, through the size of the keywords ‘micelles’, ‘nanoparticles’, ‘drug delivery’ and ‘amphiphilic block copolymers’. 2019 confirmed such evolution and ‘drug delivery’ stands as the biggest word, surrounded by strictly ...
https://www.sciencedirect.com/science/article/pii/0169409X95000312
The development of block copolymer micelles as long-circulating drug vehicles is described. As well, a recent fundamental study of block copolymer micelles, where much insight into their structures and properties has been realized, is briefly summarized in order to shed light on their properties in vivo.Author: Glen S. Kwon, Kazunori Kataoka
https://www.sciencedirect.com/topics/chemistry/micellar-drug
Copolymer micelles are rapidly becoming powerful nanomedicine platforms for cancer therapeutic applications due to their small size (10–100 nm), in vivo stability, ability to solubilize water-insoluble anticancer drugs, and prolonged blood circulation times. The drug is protected from enzymatic degradation by the micelle shell, and its biodistribution is mainly determined by the micelles surface …
https://www.sciencedirect.com/science/article/pii/S0927776599000582
This review describes the properties of block copolymer micelles which influence their efficiency as drug delivery vehicles for hydrophobic drugs. The key performance related properties we discuss are loading capacity, release kinetics, circulation time, biodistribution, size, size distribution and stability.
Searching for Block Copolymer Micelles As A Solution For Drug Delivery Problems?
You can just click the links above. The data is collected for you.
