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https://www.pharmafocusasia.com/articles/blood-brain-barrier-and-cns-drug-delivery
Blood-Brain Barrier and CNS Drug Delivery Parvin Zakeri-Milani , Faculty of Pharmacy, Tabriz University of Medical Sciences, Iran. The central nervous system is protected by barriers which control the passage of various chemical substances and microscopic objects, thereby regulating brain homeostasis.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4127280/
Jul 20, 2014 · The ATP binding cassettes (ABC) transporters are important selective elements of the blood brain barrier ( Table 2 ). These occur over the laminal plasma membrane of the brain capillary endothelium facing the vascular space [ 214] and protect against toxic effects by limiting drug delivery to the brain [ 170 ].Author: Ravi Kant Upadhyay
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648919/
Feb 02, 2012 · Introduction. Entry of blood circulating agents into the brain is highly selectively con-trolled by specific transport machineries at the blood brain barrier (BBB), whose excellent barrier restrictiveness make brain drug delivery and targeting very challenging.Author: Yadollah Omidi, Jaleh Barar
https://www.ncbi.nlm.nih.gov/pubmed/31916480
Jan 09, 2020 · The blood-brain barrier (BBB) has a significant contribution to homeostasis and protection of the CNS. However, it also limits the crossing of therapeutics and thereby complicates the treatment of CNS disorders. To overcome this limitation, the use of nanocarriers for drug delivery across the BBB has recently been exploited.Author: John J.E. Mulvihill, Eoghan M. Cunnane, Aisling M. Ross, Jason T. Duskey, Giovanni Tosi, Andreas M. ...
https://www.bookshopee.com/9781118788356/
Blood-Brain Barrier In Drug Discovery: Optimizing Brain Exposure Of Cns Drugs And Minimizing Brain Side Effects For Peripheral Drugs by Li Di on Bookshopee.com. Best Price online. Faster Shipping. Worldwide Delivery.
https://www.ncbi.nlm.nih.gov/pubmed/23609350
Blood-brain barrier structure and function and the challenges for CNS drug delivery. Abbott NJ(1). Author information: (1)BBB Group, Institute of Pharmaceutical Science, King's College London, London, UK. [email protected]: N. Joan Abbott
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