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https://pubs.acs.org/doi/10.1021/nn2037384
Oct 25, 2011 · Aptamers can bind a wide range of biomedically relevant proteins with affinities and specificities that have therapeutic utility. Although aptamers are susceptible to nuclease-mediated degradation and cannot easily cross biological barriers, specific aptamer modification can feasibly solve these problems. To address these obstacles, Lau et al. developed a general strategy for generating ...Author: Zhan Wu, Li-Juan Tang, Xiao-Bing Zhang, Jian-Hui Jiang, Weihong Tan
https://tan.chem.ufl.edu/wp-content/uploads/sites/39/pubs/important-articles/Aptamer-Modified%20Nanodrug%20Delivery%20Systems.pdf
Typical Aptamer-Modified Nanodrug Delivery Systems nanoparticles typical assembly techniques an example application single-stranded DNA (ssDNA)-single-walled carbon nanotubes (SWNTs) noncovalent modification by aromatic interactions between nucleotide bases and carbon nanotube side walls protecting single-stranded DNA during cellular delivery6
https://www.researchgate.net/publication/51738686_Aptamer-Modified_Nanodrug_Delivery_Systems
Request PDF Aptamer-Modified Nanodrug Delivery Systems Aptamers can bind a wide range of biomedically relevant proteins with affinities and specificities that have therapeutic utility.
https://www.sciencedirect.com/science/article/pii/S0142961217305409
Co-delivery of oxygen and erlotinib by aptamer-modified liposomal complexes to reverse hypoxia-induced drug resistance in lung cancer. ... Nanoparticulate drug delivery system ... Therefore, in this work, CL were selected as nano-carriers to administrate drug and PFOB together.Author: Fengqiao Li, Hao Mei, Yu Gao, Xiaodong Xie, Huifang Nie, Tao Li, Huijuan Zhang, Lee Jia
https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
Sep 19, 2018 · Nanomedicine and nano delivery systems are a relatively new but rapidly developing science where materials in the nanoscale range are employed to serve as means of diagnostic tools or to deliver therapeutic agents to specific targeted sites in a controlled manner.Author: Jayanta Kumar Patra, Gitishree Das, Leonardo Fernandes Fraceto, Leonardo Fernandes Fraceto, Estefani...
http://www.thenanoresearch.com/upload/justPDF/0898.pdf
Drug Delivery with Aptamer Modified Nanostructures Yu Yang 1 , Jingjing Liu 2 , Xiaoqi Sun 2 , Liangzhu Feng 2 , Wenwen Zhu 2 , Zhuang Liu 2 ( ), Meiwan Chen 1 ( ) 1 State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of …
http://ijpsr.com/bft-article/nano-drug-delivery-systems-a-review/?view=fulltext
CONCLUSION: Nano drug delivery systems are increasingly providing the pharmaceutical industry with solutions to formulation and opportunities for line extensions for existing drug through improved therapeutic outcomes or alternative routes of administration. As nanotechnology increasingly attracts research funding, the range of colloidal structures that can be employed in these tasks will be better …
https://www.researchgate.net/profile/Chamindri_Witharana2/publication/320416411_Drug_Delivery_Systems_A_New_Frontier_in_Nano-technology/links/59e46d3f0f7e9b97fbf05850/Drug-Delivery-Systems-A-New-Frontier-in-Nano-technology.pdf
Drug Delivery Systems: A New Frontier in Nano-technology Chamindri Witharana 1 * and Janith Wanigasekara 2 1 Senior Lecturer, Department of Biochemistry and Molecular Biology, Faculty of …
https://link.springer.com/article/10.1007%2Fs12274-015-0898-4
Nov 09, 2015 · Stimuli-activated targeted delivery systems for highly accurate treatment of tumors have received considerable attention in recent years. Herein, we reveal Upon exposure to near-infrared (NIR) laser, localized photothermal heating of the surface of those nano-agents results in dehybridization of the double-stranded DNA and uncaging of the aptamer sequence to allow specific cancer-cell targeting.Author: Yu Yang, Jingjing Liu, Xiaoqi Sun, Liangzhu Feng, Wenwen Zhu, Zhuang Liu, Meiwan Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Currently many substances are under investigation for drug delivery and more specifically for cancer therapy. Interestingly pharmaceutical sciences are using nanoparticles to reduce toxicity and side effects of drugs and up to recently did not realize that carrier systems themselves may impose risks to …Author: Wim H De Jong, Paul Ja Borm
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