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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5041385/
Subgingival irrigation with a chemotherapeutic agent, when delivered with an irrigation device, may be a beneficial adjunctive modalit. In this study, we were able to manage moderate cases, which may have needed surgical treatment, by noninvasive procedure using local drug delivery.
https://www.practicebooster.com/codepreview.asp?id=733
FDA approved subgingival delivery devices containing antimicrobial medication(s) are inserted into periodontal pockets to suppress the pathogenic microbiota. These devices slowly release the pharmacological agents so they can remain at the intended site of action in a therapeutic concentration for a sufficient length of time.
https://journals.sagepub.com/doi/abs/10.1177/10454411970080020501
Apr 01, 1997 · Subgingival Delivery of Therapeutic Agents in the Treatment of Periodontal Diseases Show all authors. W. Aubrey Soskolne. W. Aubrey Soskolne. ... Use of antimicrobial containing acrylic strips in the treatment of chronic periodontal disease. A three month follow-up study. J …Author: W. Aubrey Soskolne
https://www.sciencedirect.com/science/article/pii/S0924857998000041
Subgingival controlled release of antimicrobial agents in the treatment of periodontal disease ... The local delivery of antimicrobial therapy to periodontal pockets has the benefit of putting more drug at the target site ... the results obtained with subgingival delivery systems used as stand alone therapy have been generally comparable to SRP ...Author: G.Lee Southard, Kenneth C Godowski
https://experts.umn.edu/en/publications/the-effect-of-professional-and-home-subgingival-irrigation-with-a
The purpose of this investigation was to study the effect of a professionally applied subgingival antimicrobial agent (stannous fluoride) delivered at periodontal prophylaxis, combined with home personal subgingival delivery of an antimicrobial agent (iodine) on …Author: Wolff Lf, Bakdash Mb, Pilhlstrom Bl, Bandt Cl, Aeppli Dm
https://www.rdhmag.com/pathology/periodontitis/article/16404841/update-on-local-delivery-systems
We now have three products (five worldwide) for the delivery of subgingival antimicrobials. At first glance, this simply looks like a choice of adjuncts to supplement our current instrumentation approach. If we look closer, however, it could be an opportunity to completely change dental hygiene, resulting in far more effective therapy and much better use of our time! It`s up to us.
https://www.researchgate.net/profile/John_Cotton/publication/221690052_Subgingival_delivery_of_oral_debriding_agents_A_proof_of_concept/links/0912f50368f63cd5f0000000.pdf
Localized subgingival delivery of antimicrobial and antibiotic agents is routinely employed as adjunctive therapy for the treatment and management of periopathogens associated with periodontal ...
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