Antimicrobial Drug Delivery To The Eye

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Antimicrobial Drug Delivery to the Eye - Timothy S. Lesar ...

    https://journals.sagepub.com/doi/10.1177/106002808501900905
    Sep 01, 1985 · A major obstacle in the treatment of ocular infections is the difficulty in obtaining adequate antimicrobial drug concentration at the site of infection. This article reviews the pharmacokinetic principles of ophthalmic drug delivery as it pertains to antimicrobial therapy.Author: Timothy S. Lesar, Richard G. Fiscella

Antimicrobial drug delivery to the eye.

    https://www.ncbi.nlm.nih.gov/pubmed/3899562
    Antimicrobial drug delivery to the eye. Lesar TS, Fiscella RG. A major obstacle in the treatment of ocular infections is the difficulty in obtaining adequate antimicrobial drug concentration at the site of infection. This article reviews the pharmacokinetic principles of ophthalmic drug delivery as it pertains to antimicrobial therapy.Author: Timothy S. Lesar, Richard G. Fiscella

Review: Emerging strategies for antimicrobial drug ...

    https://www.sciencedirect.com/science/article/pii/S154201241630115X
    Instillation of eye drops is the traditional method of antimicrobial drug delivery to the cornea. Although eye drops allow easy administration by the patient, they usually have poor bioavailability due to rapid nasolacrimal drainage and limited corneal permeability.Author: Ajay Sharma, Jonathan Taniguchi

Ocular Drug Delivery

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895432/
    May 01, 2010 · Ocular drug delivery has been a major challenge to pharmacologists and drug delivery scientists due to its unique anatomy and physiology. Static barriers (different layers of cornea, sclera, and retina including blood aqueous and blood–retinal barriers), dynamic barriers (choroidal and conjunctival blood flow, lymphatic clearance, and tear dilution), and efflux pumps in conjunction pose a ...Author: Ripal Gaudana, Hari Krishna Ananthula, Ashwin Parenky, Ashim K. Mitra

Emerging strategies for antimicrobial drug delivery to the ...

    https://www.researchgate.net/publication/317412025_Emerging_strategies_for_antimicrobial_drug_delivery_to_the_ocular_surface_Implications_for_infectious_keratitis
    This review will help pharmaceutical formulators to identify different parts of the eye and the corresponding bacterial infections, ocular barriers to drug delivery, and general consideration when ...

Nanostructures for Antimicrobial Therapy ScienceDirect

    https://www.sciencedirect.com/book/9780323461528/nanostructures-for-antimicrobial-therapy
    The successful use of antibiotics is challenged by the rapid emergence of antibiotic resistance and the need for better methods of delivery. To overcome the problem of drug resistance, novel antimicrobial agents are needed to which the clinical isolates cannot easily develop resistance.

Ocular Drug Delivery System authorSTREAM

    http://www.authorstream.com/Presentation/deepscpn-2284224-ocular-drug-delivery-system/
    Oct 03, 2014 · INTRODUCTION: Ocular drug delivery system is intended for treatment of various eye disorders. Glaucoma- Timolol, pilocarpine Antimicrobial and Anti-inflamatory drugs- Steroids, Gentamycin Medication for dry eye syndrome HPMC, Ointments

Anti Microbial Bandage Contact Lens with Ocular Drug Delivery

    http://www.freepatentsonline.com/y2019/0101669.html
    Apr 04, 2019 · Anti Microbial Bandage Contact Lens with Ocular Drug Delivery. The novel device is an antimicrobial bandage contact lens (BCL) that 1) acts as a prophylactic device that prevents microbial infections in an eye using inherently antimicrobial biomaterials with nanotopography, 2) treats existing infection by dispensing antimicrobial medication at ...Author: Albert Yee, Rachel Rosenzweig, Mary Nora Dickson, Elena Liang, Szu-wen Wang

Intraocular penetration of antimicrobial agents in ...

    https://www.tandfonline.com/doi/figure/10.1517/17425240902798119
    Mar 09, 2018 · For the last three to four decades much emphasis has been placed on drug delivery systems to enhance the ocular penetration of antimicrobial agents. In order to compare ocular drug delivery strategies for ocular infections, the existing studies and methods were revisited using an extensive literature search.Author: Thirumurthy Velpandian

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