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https://www.sciencedirect.com/science/article/pii/S0165242702000727
Antigen delivery systems and immunostimulation. Abstract. The immune system evolved to free the host from invading noxious pathogens. Vaccines are inoculated as a prophylactic measure in order to program the immune system for accelerated recognition and elimination of specific pathogens.Author: Virgil E.J.C. Schijns
https://www.researchgate.net/publication/11303022_Antigen_delivery_systems_and_immunostimulation
The immunostimulating complex or 'iscom' was first described 20 years ago as an antigen delivery system with powerful immunostimulating activity.
https://www.immunology.org/public-information/bitesized-immunology/vaccines-and-therapeutics/adjuvants-particulate-antigen
Adjuvants: particulate antigen delivery systems. MF59 is an oil-in-water emulsion appearing as small, uniform oil droplets and has shown great promise as a vaccine against influenza for the elderly.
https://www.nature.com/articles/srep27206
Jun 02, 2016 · To improve antigen persistence, uptake and presentation, along with supplementing immune stimulation, co-administration of safe and efficient adjuvants is essential. The combination of delivery systems and immunopotentiating adjuvants has therefore emerged as a promising strategy for rationale vaccine design 12,13.Author: Mithun Maji, Saumyabrata Mazumder, Souparno Bhattacharya, Souparno Bhattacharya, Somsubhra Thakur Ch...
https://pubs.acs.org/doi/10.1021/mp049907k
A novel and improved vaccine delivery system and/or adjuvant is actively sought to enhance the potency of vaccines. Previously, we reported that strong antitumor immunity could be generated when a peptide antigen was incorporated into LPD (cationic liposome−polycation−pDNA) nanoparticles.Author: Zhengrong Cui, Su Ji Han, Dileep Padinjarae Vangasseri, Leaf Huang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534807/
Aug 12, 2015 · A major hurdle of developing successful and effective vaccines is to design antigen delivery systems in such a way that optimizes antigen presentation and induces broad protective immune responses. Recent advances in vector delivery technologies, immunology, vaccinology and system biology, have led to a deeper understanding of the molecular and ...Author: Maria Trovato, Piergiuseppe De Berardinis
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