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https://www.cmocro.com/news_detail/Diosynth+Biotechnology+Enters+Long-term+Commercial+Supply+Ag/55181/index.html
ACIs hold promise because they may provide patients with a meaningful survival benefit with low toxicities. Dendreon's proprietary Antigen Delivery CassetteTM technology utilizes a recombinant form of an antigen found in approximately 95 percent of prostate cancers, prostatic acid phosphatase (PAP), to stimulate a patient's own immune system.
https://www.sciencedirect.com/science/article/pii/S016836591830004X
Co-delivery of tumor antigen and dual toll-like receptor ligands into dendritic cell by silicon microparticle enables efficient immunotherapy against melanoma. ... but …Author: Motao Zhu, Xilai Ding, Ruifang Zhao, Ruifang Zhao, Xuewu Liu, Haifa Shen, Chunmei Cai, Mauro Ferrari...
http://www.healthtech.com/Conferences_Overview.aspx?id=75674&c=7679
It is comprised of autologous antigen presenting cells (APCs) stimulated ex vivo by the recombinant antigen PA2024, produced using BEVS technology. This presentation will describe the technology platform, the Antigen Delivery CassetteTM (ADC), PA2024 generation by the BEVS technology, Sipuleucel-T manufacturing, and product characterization.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808824/
The present study utilizes a unique antigen delivery system employing mitomycin C treated, antigen-pulsed allogeneic cells. We observed that such a delivery system successfully evoked an antigen-specific CD4 + Th1 response and augmented the expression of B7-1 and B7-2 co-stimulatory molecules.Author: Javed N. Agrewala, S. Suvas, V. Singh, H. Vohra
https://www.sciencedirect.com/topics/immunology-and-microbiology/antigen-presentation
In Immunology Guidebook, 2004. ANTIGEN PRESENTATION. Antigen presentation is the expression of antigen molecules on the surface of a macrophage or other antigen-presenting cell in association with MHC class II molecules when the antigen is being presented to a CD4 + helper T cell or in association with MHC class I molecules when presentation is to CD8 + cytotoxic T cells.
https://www.ncbi.nlm.nih.gov/pubmed/26279977
Aug 12, 2015 · Novel antigen delivery systems. Trovato M(1), De Berardinis P(1). Author information: (1)Maria Trovato, Piergiuseppe De Berardinis, Institute of Protein Biochemistry, National Research Council, 80131 Naples, Italy. Vaccines represent the most relevant contribution of immunology to …Author: Maria Trovato, Piergiuseppe De Berardinis
https://www.wjgnet.com/2220-3249/abstract/v4/i3/156.htm
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA ... weak immunogenicity, adverse side-effects associated with adjuvants), recent advances in vaccine technology have provided further insights for guiding vaccine design. Here, we review the current status of antigen delivery systems with emphasis on ...Author: Maria Trovato, Piergiuseppe De Berardinis
https://www.prnewswire.com/news-releases/chimeric-antigen-receptor-car-t-cell-immunotherapy--competitive-landscape-technology-and-pipeline-analysis-2017-300531216.html
Chimeric Antigen Receptor (CAR) T cell Immunotherapy- Competitive Landscape, Technology and Pipeline Analysis, 2017
https://quizlet.com/9351390/immunology-chapter-1-flash-cards/
A protein (immunoglobulin), consisting of two identical heavy chains and two identical light chains, that recognizes a particular epitope on an antigen and facilitates clearance of that antigen. Membrane-bound antibody is expressed by B cells that have not encountered antigen; secreted antibody is …
https://en.wikipedia.org/wiki/Chimeric_antigen_receptor
The diagram above represents the process of chimeric antigen receptor T-cell therapy (CAR), this is a method of immunotherapy, which is a growing practice in the treatment of cancer. The final result should be a production of equipped T-cells that can recognize and fight the infected cancer cells in the body. 1.
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