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https://www.jci.org/articles/view/97642
Targeted antigen delivery using CHP nanogel improves the antigen-presenting activity of TAMs. (A) CMS5a tumor–bearing BALB/c mice were intravenously injected with rhodamine-CHP:LPA, and 1 hour or 6 hours later, tumors were removed. The distribution of rhodamine-CHP in the tumor was observed using confocal laser microscopy.Author: Daisuke Muraoka, Daisuke Muraoka, Daisuke Muraoka, Naohiro Seo, Tae Hayashi, Yoshiro Tahara, Yoshiro...
https://advances.sciencemag.org/content/5/10/eaaw6870.full
Oct 01, 2019 · Erythrocytes or red blood cells (RBCs) represent a promising cell-mediated drug delivery platform due to their inherent biocompatibility. Here, we developed an antigen delivery system based on the nanoerythrosomes derived from RBCs, inspired by the splenic antigen-presenting cell targeting capacity of senescent RBCs. Tumor antigens were loaded onto the nanoerythrosomes by fusing …Author: Xiao Han, Shufang Shen, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu, Zhen G...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
Polymers in solid particulate vaccine delivery. Biodegaradable polymers such as PLGA,[] previously used as surgical implant and suture material is now being exploited for matrix antigen delivery.PLGA microspheres are rapidly taken up by M-cells and translocated towards …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534807/
Aug 12, 2015 · The E2 protein scaffold represents a versatile antigen delivery system (E2DISP) where antigenic determinants can be exposed on the surface of an icosahedral dodecahedral nanoparticle[61,62]. The scaffold is composed of the E2 acetyltransferase protein derived from the pyruvate dehydrogenase ...Author: Maria Trovato, Piergiuseppe De Berardinis
https://www.sciencedirect.com/science/article/pii/S016836591930118X
Another approach has been described in which 200 nm antigen loaded ZIF-8 was prepared in methanol solutions by using ultrasonication with the help of polyvinyl pyrrolidone (PVP) . In contrast to our system, this antigen delivery platform induced strong humoral but weak cellular immune response.Author: Xiaofang Zhong, Yunting Zhang, Lu Tan, Tao Zheng, Yingying Hou, Xiaoyu Hong, Guangsheng Du, Xiaoyan ...
https://www.sciencedirect.com/science/article/abs/pii/S0168365917305382
Targeted antigen delivery to dendritic cell via functionalized alginate nanoparticles for cancer immunotherapy. Author links open overlay panel Chuangnian Zhang a e 1 Gaona Shi a 1 Ju Zhang c Huijuan Song a Jinfeng Niu d Shengbin Shi a Pingsheng Huang a Yanming Wang d Weiwei Wang a Chen Li a Deling Kong a b. Show more.Author: Chuangnian Zhang, Chuangnian Zhang, Gaona Shi, Ju Zhang, Huijuan Song, Jinfeng Niu, Shengbin Shi, Pi...
https://www.nature.com/articles/s41416-020-0757-2
Feb 18, 2020 · Mizumoto, Y., Hemmi, H., Katsuda, M. et al. Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade.Author: Yuki Mizumoto, Hiroaki Hemmi, Masahiro Katsuda, Motoki Miyazawa, Yuji Kitahata, Atsushi Miyamoto, Mi...
https://www.researchgate.net/publication/336762122_Red_blood_cell-derived_nanoerythrosome_for_antigen_delivery_with_enhanced_cancer_immunotherapy
Erythrocytes or red blood cells (RBCs) represent a promising cell-mediated drug delivery platform due to their inherent biocompatibility. Here, we developed an antigen delivery system based on the ...
https://www.immunology.org/public-information/bitesized-immunology/vaccines-and-therapeutics/adjuvants-particulate-antigen
Adjuvants: particulate antigen delivery systems. Download A.ppt (561.5 KB) Download Adjuvants - particulate delivery systems (Adyuvan.pdf (215.14 KB) Rebecca Helson, London, UK . MF59 is an oil-in-water emulsion appearing as small, uniform oil droplets and has shown great promise as a vaccine against influenza for the elderly. Safety and ...
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