Antigen Delivery Dendritic Cells

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Targeted Antigen Delivery to DEC-205+ Dendritic Cells for ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3740698/
    Feb 10, 2013 · Dendritic cells (DCs) and Foxp3-expressing CD4 + regulatory T (Treg) cells play non-redundant roles in the maintenance of peripheral tolerance to self-antigens, thereby preventing fatal autoimmunity. A common hallmark of intra- and extra-thymic Treg cell lineage commitment is the induction of Foxp3 expression as a consequence of appropriate T cell receptor engagement with MHC …Author: Cathleen Petzold, Sonja Schallenberg, Joel N.H. Stern, Karsten Kretschmer

Anticancer effects of chemokine-directed antigen delivery ...

    https://www.nature.com/articles/s41416-020-0757-2
    Feb 18, 2020 · Anticancer effects of chemokine-directed antigen delivery to a cross-presenting dendritic cell subset with immune checkpoint blockade Skip to main content Thank you for visiting nature.com.Author: Yuki Mizumoto, Hiroaki Hemmi, Masahiro Katsuda, Motoki Miyazawa, Yuji Kitahata, Atsushi Miyamoto, Mi...

Targeted PLGA nano- but not microparticles specifically ...

    https://www.sciencedirect.com/science/article/pii/S0168365910001215
    Targeted PLGA nano- but not microparticles specifically deliver antigen to human dendritic cells via DC-SIGN in vitro. ... In contrast to mouse studies on targeted antigen delivery, which usually target DEC-205, our antibody recognizes DC-SIGN.Author: Luis J. Cruz, Paul J. Tacken, Remco Fokkink, Ben Joosten, Martien Cohen Stuart, Fernando Albericio, ...

Antigen delivery to dendritic cells by poly(propylene ...

    https://www.sciencedirect.com/science/article/pii/S0264410X10014192
    Vaccines aiming to activate cytotoxic T cells require cross-presentation of exogenous antigen by antigen-presenting cells (APCs). We recently developed a synthetic nanoparticle vaccine platform that targets lymph node-resident dendritic cells (DCs), capable of mounting an …Author: Sachiko Hirosue, Iraklis C. Kourtis, André J. van der Vlies, Jeffrey A. Hubbell, Melody A. Swartz

Antigen delivery to early endosomes eliminates the ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3646496/
    May 06, 2013 · Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3 + dendritic cells at cross presentation Lillian Cohn , 1 Bithi Chatterjee , 1 Filipp Esselborn , 1 Anna Smed-Sörensen , 1, 2 Norihiro Nakamura , 1 Cécile Chalouni , 1 Byoung-Chul Lee , 1 Richard Vandlen , 1 Tibor Keler , 3 Peter Lauer , 4 Dirk Brockstedt , 4 ...Author: Lillian Cohn, Bithi Chatterjee, Filipp Esselborn, Anna Smed-Sörensen, Anna Smed-Sörensen, Norihiro N...

Antigen delivery to dendritic cells shapes human CD4+ and ...

    https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1006387
    Antigen delivery to dendritic cells shapes human CD4 + and CD8 + T cell memory responses to Staphylococcus aureus. Julia Uebele, Affiliations Division of Microbiology, Paul-Ehrlich Institute, Langen, Germany, Institute for Medical Microbiology, Immunology and Parasitology (IMMIP), ...Author: Julia Uebele, Julia Uebele, Christoph Stein, Christoph Stein, Minh-Thu Nguyen, Anja Schneider, Franz...

Red blood cell–derived nanoerythrosome for antigen ...

    https://advances.sciencemag.org/content/5/10/eaaw6870.full
    Oct 01, 2019 · Erythrocytes or red blood cells (RBCs) represent a promising cell-mediated drug delivery platform due to their inherent biocompatibility. Here, we developed an antigen delivery system based on the nanoerythrosomes derived from RBCs, inspired by the splenic antigen-presenting cell targeting capacity of senescent RBCs. Tumor antigens were loaded onto the nanoerythrosomes by fusing …Author: Xiao Han, Shufang Shen, Qin Fan, Guojun Chen, Edikan Archibong, Gianpietro Dotti, Zhuang Liu, Zhen G...

Antigen delivery to early endosomes eliminates the ...

    https://rupress.org/jem/article/210/5/1049/41442/Antigen-delivery-to-early-endosomes-eliminates-the
    Lillian Cohn, Bithi Chatterjee, Filipp Esselborn, Anna Smed-Sörensen, Norihiro Nakamura, Cécile Chalouni, Byoung-Chul Lee, Richard Vandlen, Tibor Keler, Peter Lauer, Dirk Brockstedt, Ira Mellman, Lélia Delamarre; Antigen delivery to early endosomes eliminates the superiority of human blood BDCA3 + dendritic cells at cross presentation.Author: Lillian Cohn, Bithi Chatterjee, Filipp Esselborn, Anna Smed-Sörensen, Anna Smed-Sörensen, Norihiro N...

Antigen delivery by dendritic cells (Review)

    https://www.researchgate.net/publication/8187871_Antigen_delivery_by_dendritic_cells_Review
    Antigen delivery by dendritic cells (Review) ... a uniform size of ~3.4 μm can be recognized and internalized by dendritic cells (DCs). The YS-mediated antigen delivery can enhance the cellular ...

Direct Delivery of Antigens to Dendritic Cells via ...

    https://www.mdpi.com/2076-393X/4/2/8/htm
    Dendritic cells (DCs) are the most potent professional antigen presenting cells and are therefore indispensable for the control of immunity. The technique of antibody …Author: Christian H. K. Lehmann, Lukas Heger, Gordon F. Heidkamp, Anna Baranska, Jennifer J. Lühr, Alana Hof...

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