We have collected information about Antibody Delivery Cancer for you. Follow the links to find out details on Antibody Delivery Cancer.
https://www.nature.com/articles/s41587-019-0404-8
Feb 10, 2020 · Several cancer immunotherapy approaches, such as immune checkpoint blockade and adoptive T-cell therapy, boost T-cell activity against the tumor, …Author: David G. Millar, Rakesh R. Ramjiawan, Kosuke Kawaguchi, Nisha Gupta, Jiang Chen, Songfa Zhang, Takas...
https://www.ncbi.nlm.nih.gov/pubmed/32042168
Feb 10, 2020 · Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy. ... Several cancer immunotherapy approaches, such as immune checkpoint blockade and adoptive T-cell therapy, boost T-cell activity against the tumor, but these strategies are not effective in the absence of T cells specific for displayed ...Author: David G. Millar, Rakesh R. Ramjiawan, Kosuke Kawaguchi, Nisha Gupta, Jiang Chen, Songfa Zhang, Takas...
https://www.sciencedirect.com/science/article/pii/S136759311000075X
Hence, several strategies have been employed to enhance their activity. Antibody–drug conjugates (ADCs) represent one approach, where the ability to harness mAb specificity and target the delivery of a cytotoxic agent to the tumor may significantly enhance both mAb and drug activities.Author: Stephen C Alley, Nicole M Okeley, Peter D Senter
https://stm.sciencemag.org/content/11/486/eaax1720.full
Apr 03, 2019 · JAK-ing up antibody delivery to cancer Anand D. Jeyasekharan Department of Haematology-Oncology, National University Hospital and Cancer Science Institute of Singapore, National University of Singapore, 117599 Singapore.Author: Anand D. Jeyasekharan
https://clincancerres.aacrjournals.org/content/early/2020/01/24/1078-0432.CCR-19-3717
Jan 01, 2020 · Purpose: The efficacy of antibody-based therapeutics depends on successful drug delivery into solid tumors, therefore there is a clinical need to measure intratumoral antibody distribution. This study aims to develop and validate an imaging and computation platform to directly quantify and predict antibody delivery into human head and neck cancers in a clinical study. Experimental Design ...Author: Guolan Lu, Shayan Fakurnejad, Brock A. Martin, Nynke S. van den Berg, Stan van Keulen, Naoki Nishio,...
https://clincancerres.aacrjournals.org/content/25/15/4846
Aug 01, 2019 · Experimental Design: We have developed a new targeted nanomedicine based on hyaluronic acid–biocompatible nanocapsules, which allow the intracellular delivery of a specific anti-GSDMB antibody into HER2 breast cancer cells both in vitro and in vivo.Author: Ángela Molina-Crespo, Ana Cadete, David Sarrio, Manuel Gámez-Chiachio, Lidia Martinez, Kinlin Chao, ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6944323/
It is suggested that 10 000 antigens per cell is the minimum number of antigens required to ensure the selective delivery of lethal cytotoxic drugs to cancer cells . A major challenge to solid tumor therapy arises from antigen expression, which varies with tumor volume, heterogeneity, and treatment [ 13 ].Author: Samaresh Sau, Hashem O. Alsaab, Hashem O. Alsaab, Sushil Kumar Kashaw, Sushil Kumar Kashaw, Katyayan...
https://jhoonline.biomedcentral.com/articles/10.1186/1756-8722-5-70
Nov 09, 2012 · Therapeutic monoclonal antibody (TMA) based therapies for cancer have advanced significantly over the past two decades both in their molecular sophistication and clinical efficacy. Initial development efforts focused mainly on humanizing the antibody protein to overcome problems of immunogenicity and on expanding of the target antigen repertoire.Author: Michael A Firer, Gary Gellerman
https://mct.aacrjournals.org/content/13/7/1772
Jul 01, 2014 · Antibody–drug conjugates are increasingly being used for cancer therapy, but little is known about their ability to promote anticancer immunity, which may lead to long-lasting remissions. We investigated the therapeutic effect of antibody-based pharmacodelivery of cemadotin, a cytotoxic drug, and IL2, a strong proinflammatory cytokine. Using the F8 antibody, which selectively localizes to ...Author: Katrin L. Gutbrodt, Giulio Casi, Dario Neri
Searching for Antibody Delivery Cancer?
You can just click the links above. The data is collected for you.
