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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2751225/
The present study investigates the use of novel anionic lipoplexes composed of physiological components for plasmid DNA delivery into mammalian cells in vitro. Liposomes were prepared from mixtures of endogenously occurring anionic and zwitterionic lipids, ...Author: Siddhesh D. Patil, David G. Rhodes, Diane J. Burgess
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Various anionic liposomes have been characterized for gene delivery in a small number of cell types including CHO cells and primary hippocampal neurons [8, 66, 68, 69]. While such investigations are novel, overall knowledge regarding anionic lipofection is as yet limited due to a lack of extensive testing; DNA entrapment in anionic liposomes is ...Author: Daniel A. Balazs, Wt. Godbey
https://www.hindawi.com/journals/jdd/2011/326497/
Various anionic liposomes have been characterized for gene delivery in a small number of cell types including CHO cells and primary hippocampal neurons [8, 66, 68, 69]. While such investigations are novel, overall knowledge regarding anionic lipofection is as yet limited due to a lack of extensive testing; DNA entrapment in anionic liposomes is ...Author: Daniel A. Balazs, Wt. Godbey
https://www.sciencedirect.com/science/article/abs/pii/S0168365909000820
Anionic lipoplexes (anionic liposomes/DNA/Ca 2+) show higher transfection efficiency and lower cytotoxicity compared to the commercially available cationic lipoplex, Lipofectamine2000/DNA in CHO-K1 cells in presence of serum.. Download : Download full-size image
https://www.researchgate.net/publication/51049116_Liposomes_for_Use_in_Gene_Delivery
Liposomes for Use in Gene Delivery.pdf. ... used for gene delivery, while the use of anionic liposomes. has been fairly restricted to the delivery of other therapeutic. macromolecules [14].
https://www.researchgate.net/publication/7471375_Cationic_liposomes_for_gene_delivery
Anionic liposomes exhibiting pH-sensitivity h ave been shown to mediate gene transfer , but, similarly to other non- cationic formulations, the y pr esent major disadvantages when
https://pubs.acs.org/doi/10.1021/mp900151k
Despite remarkable progress in the research of both viral and nonviral gene delivery vectors, the drawbacks in each delivery system have limited their clinical applications. Therefore, one of the concepts for developing novel vectors is to overcome the limitations of individual vectors by combining them. In the current study, adenoviral vectors were formulated with anionic liposomes to protect ...Author: Zhirong Zhong, Sanjun Shi, Jianfeng Han, Zhirong Zhang, Xun Sun
https://en.wikipedia.org/wiki/Cationic_liposome
Cationic liposomes are structures that are made of positively charged lipids and are increasingly being researched for use in gene therapy due to their favorable interactions with negatively charged DNA and cell membranes. Upon interacting with negatively charged DNA, cationic liposomes form clusters of aggregated vesicles. At a critical density the DNA is condensed and becomes encapsulated ...
https://www.slideshare.net/pratibhaSharma97/liposome-mediated-gene-delivery
Jun 26, 2018 · liposome mediated gene delivery is the way of transfering gene into the liposome to mediate gene into the cell and perform its desired function. ... Liposomes can be classified as either 1.Cationic liposome 2.Anionic liposome ... , pH-sensitive liposomes are considered as potential gene delivery vehicles than the cationic liposomes.
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