Amphiphilic Block Copolymer Micelles For Nanoscale Drug Delivery

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Amphiphilic block copolymer micelles for nanoscale drug ...

    https://onlinelibrary.wiley.com/doi/abs/10.1002/ddr.20063
    Amphiphilic block copolymer micelles for nanoscale drug delivery ... Coupled with novel strategies toward controlled release of drug, nanoscale ABC micelles have tremendous potential for the targeting of antitumor agents, many of which are poorly water soluble and possess dose‐limiting toxicity. ... O.N. Iakubchak, D.O. Klymchuk, M.Ya ...Author: Glen S. Kwon, M. Laird Forrest

Amphiphilic block copolymer micelles for nanoscale drug ...

    https://www.researchgate.net/publication/229727598_Amphiphilic_block_copolymer_micelles_for_nanoscale_drug_delivery
    Amphiphilic block copolymers can assemble into supramolecular core-shell structures, termed ABC micelles, that have proven utility in drug delivery, particularly for drug solubilization.

Amphiphilic block copolymer micelles for nanoscale drug ...

    https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.20063
    May 11, 2006 · Amphiphilic block copolymers can assemble into supramolecular core‐shell structures, termed ABC micelles, that have proven utility in drug delivery, …Author: Glen S. Kwon, M. Laird Forrest

Advanced drug delivery devices via self-assembly of ...

    https://www.sciencedirect.com/science/article/pii/S0169409X01002228
    One class of drug delivery vehicle that has received widespread attention over the past decades is micelles formed by self-assembly of amphiphilic block copolymers in aqueous solution , , . Block copolymer micelles are of interest for drug delivery applications for a number of reasons.Author: Annette Rösler, Guido W.M Vandermeulen, Harm-Anton Klok

Block Copolymer Micelles for Drug Delivery

    https://www.rug.nl/research/zernike/education/topmasternanoscience/ns190solmaz.pdf
    Amphiphilic block copolymer micelles for drug delivery applications are significant mainly in two aspects. First of all, hydrophobic drug molecules can be loaded to the micelle core to be carried to the target with a higher solubility than its intrinsic solubility in bloodstream which shows hydrophilic properties.

Block copolymer micelles for drug delivery: design ...

    https://www.sciencedirect.com/science/article/pii/S0169409X00001241
    Block copolymer micelles for drug delivery: design, characterization and biological significance. ... importance in this regard is the establishment of a novel and effective synthetic route for end-functionalized amphiphilic block copolymers with appreciable biocompatibiity and biodegradability, allowing conjugation of the pilot-molecules at ...Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki

Micelles as drug carriers

    https://www.unmc.edu/pharmacy/faculty/pharmaceutical-sciences/docs/v5.pdf
    Amphiphilic di-block (hydrophilic-hydrophobic) or tri-block (hydrophilic-hydrophobic-hydrophilic) copolymers are most commonly used to prepare self-assembled polymer micelles for drug delivery,9,15,16 although the use of graft copolymers has been reported.17-19 For drug delivery purposes, the individual ure designed to be nimers a

Amphiphilic block copolymers in drug delivery: advances in ...

    https://www.researchgate.net/publication/327918925_Amphiphilic_block_copolymers_in_drug_delivery_advances_in_formulation_structure_and_performance
    Download Citation Amphiphilic block copolymers in drug delivery: advances in formulation structure and performance Introduction: Nanostructured delivery vehicles can address key challenges ...

Doxorubicin-loaded aromatic imine-contained amphiphilic ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445873/
    Doxorubicin-loaded aromatic imine-contained amphiphilic branched star polymer micelles: synthesis, self-assembly, and drug delivery Liang Qiu , Chun-Yan Hong , and Cai-Yuan Pan Chinese Academy of Sciences Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, University of Science and Technology of China, Hefei ...Author: Liang Qiu, Chun-Yan Hong, Cai-Yuan Pan

Theranostic Unimolecular Micelles Based on Brush-Shaped ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4163544/
    Dec 24, 2014 · Brush-shaped amphiphilic block copolymers were conjugated with a monoclonal antibody against CD105 (i.e., TRC105) and a macrocyclic chelator for 64 Cu-labeling to generate multifunctional theranostic unimolecular micelles. The backbone of the brush-shaped amphiphilic block copolymer was poly(2-hydroxyethyl methacrylate) (PHEMA) and the side chains were poly(l-lactide)-poly(ethylene …Author: Jintang Guo, Hao Hong, Guojun Chen, Sixiang Shi, Tapas R. Nayak, Charles P. Theuer, Todd E. Barnhart...

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