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https://www.sciencedirect.com/science/article/pii/0168365993901722
Both virus 121 and lipoproteins are regarded as sophisticated nanoscopic vehicles in biological systems. Self assemblage of amphiphilic block copolymers Nanoscopic vehicles having a microcontainer separate from the outer environment are prom- ising for site-specific delivery of …Author: Kataoka Kazunori, S Kwon Glenn, Yokoyama Masayuki, Okano Teruo, Sakurai Yasuhisa
https://www.sciencedirect.com/science/article/pii/B9780128136270000107
The hydrophobic segments of the copolymers constitute the cores of the micelles that are used for the solubilization of drug molecules. Thus, the hydrophobic cores of micelles are used for solubilization of lipophilic drugs and act as cargo sites for their delivery (Bromberg, 2008, Mourya et al., 2011).Author: Muhammad Imran, Muhammad R. Shah, Shafiullah
https://www.sciencedirect.com/science/article/pii/S0022354916312849
The functional properties of micelles based on amphiphilic block copolymers (ABCs) render them ideal for encapsulation and delivery of hydrophobic drugs. ABCs consist of at least two regions of distinct chemical nature that undergo phase separation as a result of chain association in solvents that selectively dissolve one of the blocks.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon
https://onlinelibrary.wiley.com/doi/full/10.1002/jps.10397
The functional properties of micelles based on amphiphilic block copolymers (ABCs) render them ideal for encapsulation and delivery of hydrophobic drugs. ABCs consist of at least two regions of distinct chemical nature that undergo phase separation as a result of chain association in solvents that selectively dissolve one of the blocks.Author: Monica L. Adams, Afsaneh Lavasanifar, Glen S. Kwon
https://onlinelibrary.wiley.com/doi/abs/10.1002/ddr.20063
Amphiphilic block copolymers can assemble into supramolecular core‐shell structures, termed ABC micelles, that have proven utility in drug delivery, particularly for drug solubilization.Author: Glen S. Kwon, M. Laird Forrest
https://www.rug.nl/research/zernike/education/topmasternanoscience/ns190solmaz.pdf
Amphiphilic block copolymer micelles have been the focus of research for the last decades because of the promising properties as nano size drug delivery vehicles. In polar aqueous milieu, copolymers self assemble into micelle structures which consist of hydrophilic corona and hydrophobic core regions.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3226903/
Dec 06, 2011 · Amphiphilic block copolymers are capable of solubilizing and encapsulating lipophilic compounds within a hydrophobic core, thereby, enhancing bioavailability and facilitating drug delivery. 1–7 In aqueous solution, amphiphilic block copolymers composed of hydrophilic and hydrophobic chains can undergo self-assembly into polymeric micelles. It enables amphiphilic block copolymers to …Author: Wookhyun Kim, Jiantao Xiao, Elliot L. Chaikof
https://www.sciencedirect.com/science/article/pii/S0169409X00001241
Block copolymers with amphiphilic character, having a large solubility difference between hydrophilic and hydrophobic segments, are known to assemble in an aqueous milieu into polymeric micelles with a mesoscopic size range , , , . These micelles have a fairly narrow size distribution and are characterised by their unique core–shell architecture, where hydrophobic segments are segregated from the …Author: Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki
https://www.mdpi.com/2073-4360/12/4/869/htm
The word cloud of 2009 also shows the growing concerns about the behavior of block copolymers in solution, through the size of the keywords ‘micelles’, ‘nanoparticles’, ‘drug delivery’ and ‘amphiphilic block copolymers’. 2019 confirmed such evolution and ‘drug delivery’ stands as the biggest word, surrounded by strictly ...
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