We have collected information about Albumin Gene Delivery for you. Follow the links to find out details on Albumin Gene Delivery.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5449975/
Apr 28, 2017 · Albumin, although not considered a gene delivery vector per se, is often utilized to assist other molecules in the delivery of their gene cargo and is usually obtained from either bovine serum albumin (BSA) or human serum albumin (HSA) . Albumin is a major blood plasma protein that is easily modified because of the many reactive groups on the protein surface.Author: Michael K. Riley, Wilfred Vermerris
https://www.longdom.org/open-access/characterization-of-human-serum-albumin-facilitated-lipofection-gene-delivery-strategy-2157-7013.1000108.pdf
imperative to understand the gene transfer mechanism. To date, there is only limited understanding of the cellular and molecular mechanisms of cationic lipid-mediated gene transfer [3]. This communication reports characterization of the mechanism of an albumin-facilitated lipofection gene delivery strategy.
https://www.mdpi.com/1999-4923/11/11/608/htm
In the present study, a simple cationic human serum albumin (CHSA)-based gene-delivery system containing nuclear localization signals (NLSs) was constructed to conquer the limitations. CHSA/NLS/plasmid DNA (pDNA) complexes were prepared and characterized by Hoechst 33258 intercalation, gel retardation assay, morphological analysis, circular dichroism (CD) spectroscopy, …Author: Guannan Guan, Baohui Song, Jie Zhang, Kang Chen, Haiyang Hu, Mingyue Wang, Dawei Chen
https://www.sciencedirect.com/science/article/pii/S016836590300302X
Since nanoparticles are well suited to traverse cellular membranes and to mediate drug or gene delivery,, we developed DNA-bound human serum albumin (HSA) nanoparticles to which targeting moieties can be attached, additionally. HSA is an abundant protein that is widely used as a material for microsphere and nanosphere preparation.Author: Stephanie Rhaese, Hagen von Briesen, Helga Rübsamen-Waigmann, Jörg Kreuter, Klaus Langer
https://utsouthwestern.pure.elsevier.com/en/publications/echocardiographic-destruction-of-albumin-microbubbles-directs-gen
Background - The noninvasive, tissue-specific delivery of therapeutic agents to the heart would be a valuable clinical tool. This study addressed the hypothesis that albumin-coated microbubbles could be used to effectively deliver an adenoviral transgene to rat myocardium by ultrasound-mediated microbubble destruction.Author: Ralph V. Shohet, Shuyuan Chen, Yan Ting Zhou, Zhuowei Wang, Robert S. Meidell, Roger H Unger, Paul A...
https://www.ahajournals.org/doi/10.1161/01.CIR.101.22.2554
Background —The noninvasive, tissue-specific delivery of therapeutic agents to the heart would be a valuable clinical tool. This study addressed the hypothesis that albumin-coated microbubbles could be used to effectively deliver an adenoviral transgene to rat myocardium by ultrasound-mediated microbubble destruction.Author: Ralph V. Shohet, Shuyuan Chen, Yan Ting Zhou, Zhuowei Wang, Robert S. Meidell, Roger H Unger, Paul A...
https://www.sciencedirect.com/science/article/pii/S0378517301007657
Aug 28, 2001 · Cationized human serum albumin (cHSA) could serve as a potential non-viral vector system for gene delivery. Native human serum albumin was cationized by covalent coupling of hexamethylenediamine to the carboxyl groups resulting in a shift …Author: Dagmar Fischer, Thorsten Bieber, Sabine Brüsselbach, Hans-Peter Elsässer, Thomas Kissel
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4391875/
Work to date, on using albumin as a carrier for gene delivery, has focused on the covalent modification of the albumin molecule to synthesize cationized albumin (CA) or on the complexation of human serum albumin (HSA) with cationic polymers, to enhance DNA complexation and cell transfection.Author: Elena Nicolì, Elena Nicolì, Marie Isabel Syga, Michela Bosetti, V. Prasad Shastri
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168126/
As viral vectors comprise the risk of immune and inflammatory responses, human serum albumin (HSA) nanoparticles were found to represent a safer and more convenient alternative. Their ability to cross the blood-brain barrier (BBB) and deliver drugs into the brain in order to enhance gene-based therapy has been previously demonstrated.Author: Monica Langiu, Miriam Dadparvar, Jörg Kreuter, Mika O. Ruonala
https://www.ncbi.nlm.nih.gov/pubmed/17178885
Dec 15, 2006 · Cationic albumin-conjugated pegylated nanoparticles allow gene delivery into brain tumors via intravenous administration. 1. Cancer Res. 2006 Dec 15;66(24):11878-87. Cationic albumin-conjugated pegylated nanoparticles allow gene delivery …Author: Wei Lu, Qing Sun, Jin Wan, Zhenjue She, Xin-Guo Jiang
Searching for Albumin Gene Delivery?
You can just click the links above. The data is collected for you.
