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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3059826/
Sep 28, 2010 · Nevertheless, an optimized aerosol drug delivery system for mechanically ventilated infants still does not exist. Increasing interest in this form of drug delivery requires more controlled and focused research of drug/device combinations appropriate for the neonatal population.Author: Jan Mazela, Richard A. Polin
https://www.aarc.org/wp-content/uploads/2018/03/aersol-guides-for-rts.pdf
A Guide to Aerosol Delivery Devices for Respiratory Therapists, 4th Edition The Science of Aerosol Drug Delivery Aerosols exist everywhere there is gas to breathe. From pollen and spores, to smoke and pollution, to man-made chemicals, the aerosol category includes any fine liquid orFile Size: 1MB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978620/
Aug 08, 2016 · Therefore, it is necessary to critically assess each interface and understand its advantage and disadvantages in aerosol drug delivery to neonates and pediatrics. The purpose of this paper is to provide a critical assessment of drug delivery interfaces used for the treatment of children with pulmonary diseases by emphasizing advantages and ...Author: Arzu Ari
http://c.aarc.org/marketplace/reference_articles/06.00.0646.pdf
ing disorder, (3) the aerosol delivery system and use of the delivery system.8–10 Information regarding inhaled mass, lung deposition, and regional distribution of aerosolized medication is limited in neonates and young children. Data from in vitro models, animal studies, and in vivo infant studies indicate that aerosol delivery efficiency is ...Author: Cynthia H Cole
https://www.aarc.org/wp-content/uploads/2014/08/12.95.1325.pdf
neonates and may require dose adjustments.(13-16) This guideline addresses characteristics of an aerosol delivery system. This guideline provides recommendations to assist the clinician in selecting an aerosol delivery device based on the patient's ability. Identifying the …
http://rc.rcjournal.com/content/60/6/894
Jun 01, 2015 · Clinical Controversies in Aerosol Therapy for Infants and Children. Robert M DiBlasi. ... Assuming similar bias flows and ventilator designs, the best explanation for differences in drug delivery between neonates and larger simulated pediatric and adult patient models is the proportionately smaller volumes, shorter inspiratory times, and faster ...
http://onlinelibrary.wiley.com/doi/10.1002/ppul.23123/abstract
Oct 19, 2015 · Objectives: The purpose of this study was to compare aerosol delivery via HFNC, bubble CPAP, and SiPAP in a model of a simulated spontaneously breathing preterm infant. Working hypothesis: The types of CPAP systems and nebulizer positions used during aerosol therapy will impact aerosol deposition in simulated spontaneously breathing infants.
http://rc.rcjournal.com/content/59/3/443
Mar 01, 2014 · The aerosol delivery and loss in the devices and circuit was measured with radio-labeled technetium and scintigraphy. They found that placing the nebulizer closer to the patient significantly improved aerosol delivery. The majority of the drug loss occurred in the inspiratory limb and nebulizer when the nebulizer was located at the humidifier.Author: Jan Mazela
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