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https://www.pharma-iq.com/pre-clinical-discovery-and-development/articles/multiparticulate-drug-delivery-systems
Multiparticulate Drug Delivery Systems Multiparticulates or multiple unit dosage forms are the discrete, small, repetitive units of drug particles which may or may not possess similar drug release pattern. They can be tailored for pulsatile, controlled and or delayed, targeted drug release depending upon the polymer employed in fabrication.
http://www.bioline.org.br/pdf?pr08028
multiparticulate drug delivery systems are especially suitable for achieving controlled or delayed release. oral formulations with low risk of dose dumping, flexibility of blending to attain different release patterns. as well as reproducible and short gastric residence time.
https://www.slideshare.net/bknanjwade/multiparticulate-drug-delivery-systems
Jan 02, 2015 · Multiparticulate Drug Delivery Systems There are many reasons for formulating a drug as a multiparticulate system for example, to facilitate disintegration in the stomach, or to provide a convenient, fast disintegrating tablet that dissolves in water before swallowing which can aid compliance in older patients and children. Multiparticulate systems show better reproducible pharmacokinetic …
https://pdfs.semanticscholar.org/cba9/6b59f82c82e2782f945554fd6b41e1ed25ff.pdf
multiparticulate drug delivery systems are specifically suitable for achieving controlled or delayed release oral formulations with smallest amount risk of dose dumping, flexibility of combination to achieve different release patterns with reproducible and little
https://www.springer.com/gp/book/9781493970100
Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery.
https://www.sciencedirect.com/science/article/pii/B9780128157992000162
Multiparticulate drug delivery systems also facilitate the controlled absorption and taste-masking benefits. In the pharmaceutical formulation development, QbD plays an important role. It is well-organized risk-based approach with predefined objectives, process understanding, and control.Author: Saquib Hasnain, Syed Anees Ahmed, Sarwar Beg, Mohammad Tahir Ansari, Amit Kumar Nayak
https://www.researchgate.net/publication/281098252_A_REVIEW_ON_EXTENDED_RELEASE_DRUG_DELIVERY_SYSTEM_AND_MULTIPARTICULATE_SYSTEM
Recent trends indicate that multiparticulate drug delivery systems are especially suitable for achieving extended release oral formulations with low risk of dose dumping, flexibility of blending to...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673516/
Nov 02, 2015 · Multiparticulate drug delivery systems Multiparticulate products are expected to provide improved patient acceptability over single-unit solid dosage forms (i.e., tablets and capsules) by dint of their reduced size and thus improved ease of swallowing plus the increased dose flexibility provided by their multi-unit composition.Author: Felipe L Lopez, Terry B Ernest, Catherine Tuleu, Mine Orlu Gul
https://www.jgtps.com/admin/uploads/YqxI0h.pdf
the drug release, and to reduce or eliminate gastrointestinal tract irritation. In addition, multiparticulate delivery systems spread out more uniformly in the gastrointestinal tract. This results in more reproducible drug absorption and reduces local irritation when compared to single-unit dosage formsFile Size: 1MB
https://www.researchgate.net/publication/281282862_Advantage_and_Disadvantage_in_Drug_Delivery_Systems
Apr 10, 2011 · In this study, advantages and disadvantages of the preparation and implementation stages of drug formulations, as well as their detection systems have been compared each other. Conclusion of this review, we found that solid lipid nanoparticles the …
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