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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3255397/
Mucoadhesive delivery systems offer several advantages over other oral controlled release systems by virtue of prolongation of residence time of drug in gastrointestinal tract (GIT). Targeting and localization of the dosage form at a specific site.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3053525/
Drug delivery through the oral mucosa has proven particularly useful and offers several advantages over other drug delivery systems including bypassing hepatic first-pass metabolism, increasing the bioavailability of drugs, improved patient compliance, excellent accessibility, unidirectional drug flux, and improved barrier permeability compared, for example, to intact skin.[81,82] The oral cavity has …
https://www.researchgate.net/publication/221750117_Mucoadhesive_drug_delivery_system_An_overview
Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of ...
https://link.springer.com/article/10.1007%2Fs11094-009-0271-6
Aug 19, 2009 · This review addresses contemporary mucoadhesive drug delivery systems. The use of hydrophilic polymers increases the retention time of the delivery system on mucosal tissues, leading to the gradual release of the active ingredient and better tolerance by the patient.Author: E. A. Kharenko, N. I. Larionova, N. B. Demina
https://www.pharmatutor.org/articles/oral-mucoadhesive-drug-delivery-systems-review
ADVANTAGES OF ORAL MUCOADHESIVE DRUG DELIVERY SYSTEMS 1. Prolongs the residence time of the dosage form at the site of absorption, hence 2. increases the bioavailability. 3. Excellent accessibility, rapid onset of action. 4. Rapid absorption because of enormous blood supply and good blood flow rates 5.
https://www.researchgate.net/publication/285943683_Mucoadhesive_drug_delivery_Mechanism_and_methods_of_evaluation
The appropriate polymer choice for local mucoadhesive drug delivery relies on a combination of (1) the polymer's chemical reactivity and stereochemistry, (2) its molecular weight and concentration, (3) its side group flexibility and steric hindrance,...
http://www.authorstream.com/Presentation/aSGuest30531-266860-mucoadhesive-drug-delivery-systems-muco1-science-technology-ppt-powerpoint/
Nov 06, 2009 · Conclusion The mucoadhesive drug delivery offers several advantages for controlled drug delivery. The mucosa is well supplied with both vascular and lymphatic drainage. The mucous membrane has a large surface area and is well suited for a retentive device and appears to be acceptable to patients.
http://www.scielo.br/pdf/bjps/v46n1/02.pdf
Drug actions can be improved by developing new drug delivery systems, such as the mucoadhesive system. These systems remain in close contact with the absorption tissue, the mucous membrane, releasing the drug at the action site leading to a bioavailability increase and both local and systemic effects.
http://www.earthjournals.in/crps_148.pdf
Mucoadhesive drug delivery gives rapid absorption and good bioavailability due to its considerable surface area and high blood flow. Drug delivery across the mucosa
https://www.slideshare.net/MUHEEM_007/mucoadhesive-drug-delivery-system
Feb 24, 2013 · Types of Drug delivery systems:Depending upon the route of administration of the mucoadhesive drugs they are different types .They are 1)Buccal delivery system 2)Sub lingual delivery system 3)Vaginal delivery system 4)Rectal delivery system 5)Nasal delivery system 6)Ocular delivery system 7)Gastro intestinal delivery system 6. ADVANTAGES- MDDS offer several advantages over …
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