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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900005/
Jan 01, 2014 · Introduction. T he adenovirus, an 80–100 nm, nonenveloped, icosahedral capsid, double-stranded DNA virus, is a well-known cause of respiratory tract infections (Ginsberg, 1984).Adenovirus infection in humans usually is mild, but in immunocompromised individuals, it can be life threatening. The adenovirus was first isolated from human adenoids in 1953.Author: Ronald G. Crystal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679213/
May 15, 2009 · In conclusion, it is possible to deliver BLM with the aid of a VLP, Ad Dd, in order to significantly improve drug bioavailability. These experiments open new vistas for improved delivery of impermeant labile drugs, bringing us closer to in vivo use of adenovirus dodecahedron as a …Author: Monika Zochowska, Agnieszka Paca, Guy Schoehn, Jean-Pierre Andrieu, Jadwiga Chroboczek, Jadwiga Chro...
https://www.nature.com/articles/s41573-019-0012-9
Feb 01, 2019 · Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in …Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
https://www.researchgate.net/publication/24425539_Adenovirus_Dodecahedron_as_a_Drug_Delivery_Vector
Adenovirus Dodecahedron, as a Drug Delivery Vector Article (PDF Available) in PLoS ONE 4(5):e5569 · February 2009 with 82 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S0142961211010805
Tumor-targeted drug delivery is an attractive strategy in cancer treatment. Our previous study demonstrated that modified adenovirus has strong tumor targeting ability …Author: Lingling Shan, Lingling Shan, Sisi Cui, Changli Du, Shunan Wan, Zhiyu Qian, Samuel Achilefu, Yueqing...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005569
The latter can affect up to nearly 50% of the total patient population, out of which 3% will die. We propose to improve BLM delivery by tethering it to an efficient delivery vector. Adenovirus (Ad) dodecahedron base (DB) is a particulate vector composed of 12 copies …Author: Monika Zochowska, Agnieszka Paca, Guy Schoehn, Jean-Pierre Andrieu, Jadwiga Chroboczek, Jadwiga Chro...
https://www.sciencedirect.com/topics/medicine-and-dentistry/adenovirus-vector
The advantages of adenovirus vectors for delivery of antigens from other pathogens for induction of protective antibody responses are numerous because they interact with innate sensor drive maturation of antigen-presenting cells and do not require addition of adjuvants. E1-deleted adenoviral vectors are safe at immunogenic doses.
https://en.wikipedia.org/wiki/Viral_vector
Viral vectors are tools commonly used by molecular biologists to deliver genetic material into cells.This process can be performed inside a living organism or in cell culture ().Viruses have evolved specialized molecular mechanisms to efficiently transport their genomes inside the cells they infect. Delivery of genes, or other genetic material, by a vector is termed transduction and the ...
https://www.nature.com/articles/3301115
Over the last 3 years, there has been a dramatic increase in research on adenovirus targeting. In 1997, at the first Cold Spring Harbor meeting on vector targeting strategies for therapeutic gene ...
https://www.liebertpub.com/doi/abs/10.1089/hum.2004.15.1157
Jan 04, 2005 · Gene therapy is a clinical strategy that may potentially treat an array of genetic and nongenetic diseases, as well as a novel method for drug delivery and vaccination. To these ends, adenovirus vectors are a promising means to deliver specific genes of interest into the patient.Author: Daniel A. Muruve
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