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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900005/
Jan 01, 2014 · T he adenovirus, an 80–100 nm, nonenveloped, icosahedral capsid, double-stranded DNA virus, is a well-known cause of respiratory tract infections (Ginsberg, 1984). Adenovirus infection in humans usually is mild, but in immunocompromised individuals, it can be life threatening. The adenovirus was first isolated from human adenoids in 1953.Author: Ronald G. Crystal
https://www.takarabio.com/learning-centers/gene-function/viral-transduction/recombinant-virus-comparison
However, selecting the best viral gene delivery system for your experimental aim can be challenging. Use the tables below to compare the characteristics of lentivirus, retrovirus, adenovirus, and adeno-associated virus (AAV), and select the best viral transduction system for your experiment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2951029/
Production of adenovirus vectors and their use as a delivery system for influenza vaccines. ... Patel A, Tran KN, et al. Nasal delivery of an adenovirus-based vaccine bypasses pre-existing immunity to the vaccine carrier and improves the immune response in mice. PLoS One. 2008; 3:e3548.Author: Sai V Vemula, Suresh K Mittal
https://www.thermofisher.com/us/en/home/references/protocols/proteins-expression-isolation-and-analysis/adenovirus-protocol/virapower-adenoviral-expression-system.html
Components of the ViraPower™ Adenoviral Expression System The ViraPower™ Adenoviral Expression System facilitates highly efficient, in vitro or in vivo delivery of a target gene to dividing and non-dividing mammalian cells using a replication-incompetent adenovirus. Based on the secondgeneration vectors developed by Bett et al., 1994, the ViraPower™ Adenoviral Expression System takes ...
https://www.liebertpub.com/doi/10.1089/hum.2019.127
Dec 16, 2019 · However, gene delivery to kidney cells is inefficient. This is due, in part, to the fact that the kidney excludes molecules above 50 kDa and that most gene delivery vectors are megaDaltons in mass. We compared the ability of adeno-associated virus (AAV), adenovirus (Ad), and lentiviral (LV) vectors to deliver genes to renal cells.Author: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry
https://cdn.gelifesciences.com/dmm3bwsv3/AssetStream.aspx?mediaformatid=10061&destinationid=10016&assetid=21405
Adenovirus-based vectors have been widely evaluated as vaccine delivery system in preclinical and clinical studies of various infectious diseases (1). Adenovirus has also been extensively explored as a viral vector for gene therapy and as an oncolytic virus. Several generations of recombinant adenovirus vectors have been developed to enhance
https://www.sciencedirect.com/science/article/pii/S2352304217300272
There has been a long-lasting interest in using viral vectors, especially adenoviral vectors, to deliver therapeutic genes for the past two decades. Among all currently available viral vectors, adenovirus is the most efficient gene delivery system in a broad range of cell and tissue types.Author: Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Ruyi Zhang, Xinyi Yu, Xinyi Yu, Evan M. Farina, Shujuan Y...
https://www.agilent.com/cs/library/usermanuals/public/240009.pdf
AdEasy Adenoviral Vector System 3 INTRODUCTION Recombinant adenoviruses are a versatile tool for gene delivery and expression. Several features of adenovirus biology have made such viruses the vectors of choice for certain applications. For example, adenoviruses are capable of infecting a broad range of cell types and infection is not
https://www.sciencedirect.com/science/article/pii/S0003269706008566
Monitoring the homogeneity of adenovirus preparations (a gene therapy delivery system) using analytical ultracentrifugation. ... experimental method development and minimal opportunity for the introduction of artifacts or perturbations of the system while offering the ability to extract a wealth of information.Author: Steven A. Berkowitz, John S. Philo
https://www.pnas.org/content/110/10/E869
Mar 05, 2013 · Development of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adapters. Birgit Dreier, Annemarie Honegger, Christian Hess, Gabriela Nagy-Davidescu, Peer R. E. Mittl, Markus G. Grütter, Natalya Belousova, Galina Mikheeva, Victor Krasnykh, and Andreas Plückthun.Author: Birgit Dreier, Annemarie Honegger, Christian Hess, Gabriela Nagy-Davidescu, Peer R. E. Mittl, Markus...
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