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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3900005/
Jan 01, 2014 · Worldwide, adenovirus vectors are the most common vector used in clinical trials: to date, there have been 476 human gene therapy studies that have been initiated using adenovirus vectors, representing 23.5% of all gene therapy trials (Journal of Gene Medicine, 2013).Author: Ronald G. Crystal
https://www.thermofisher.com/us/en/home/technical-resources/technical-reference-library/protein-expression-support-center/adenoviral-gene-delivery-support/adenoviral-gene-delivery-support-getting-started.html
Find answers to commonly asked questions related to adenoviral gene delivery for mammalian expression, ranging from setting up of the experiment to biosafety features, cloning, adenovirus production, storage and amplification of adenoviral stocks, viral titering, transduction, and analysis of …
https://www.liebertpub.com/doi/10.1089/hum.2019.127
Dec 16, 2019 · There are many kidney diseases that might be addressed by gene therapy. However, gene delivery to kidney cells is inefficient. This is due, in part, to the fact that the kidney excludes molecules above 50 kDa and that most gene delivery vectors are megaDaltons in mass.Author: Jeffrey D. Rubin, Tien V. Nguyen, Kari L. Allen, Katayoun Ayasoufi, Michael A. Barry
https://www.nejm.org/doi/full/10.1056/NEJM199605023341809
Adenoviruses as Gene-Delivery Vehicles. James M. Wilson, M.D., Ph.D. This article has no abstract; the first 100 words appear below. For gene therapy to realize its clinical potential, there must be efficient and safe strategies of delivering therapeutic genes to somatic cells in vivo.Author: James M. Wilson
https://www.sciencedirect.com/science/article/pii/S2352304217300272
Adenovirus-mediated gene delivery in regenerative medicine. The use of adenoviral vectors for genetic engineering has opened new areas of investigation in most areas of medicine. From basic science laboratories to multi-center clinical trials, this promising field has captured the attention of the scientific community.Author: Cody S. Lee, Elliot S. Bishop, Ruyi Zhang, Ruyi Zhang, Xinyi Yu, Xinyi Yu, Evan M. Farina, Shujuan Y...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862356/
Aug 15, 2006 · Gene Delivery to the Spinal Cord: Comparison Between Lentiviral, Adenoviral, and Retroviral Vector Delivery Systems ... This strategy likely eliminates only one cause for the downregulation after adenoviral gene delivery as later downregulation may still occur due to a delayed immune response, or cell death.Author: Ahmed A. Abdellatif, Jennifer L. Pelt, Richard L. Benton, Russell M. Howard, Pantelis Tsoulfas, Peip...
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