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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6927556/
Adeno-associated virus (AAV) vectors are the leading platform for gene delivery for the treatment of a variety of human diseases. Recent advances in developing clinically desirable AAV capsids, optimizing genome designs and harnessing revolutionary biotechnologies have contributed substantially to the growth of the gene therapy field.Author: Dan Wang, Phillip W. L. Tai, Guangping Gao
https://www.sciencedirect.com/science/article/pii/S0169409X97000240
1. Introduction. Adeno-associated virus (AAV) shows significant potential as a gene delivery system. Although it is ubiquitous in its distribution, with approximately 85% of the adult USA population seropositive for the virus , it has never been associated with clinical disease.Not only is AAV non-pathogenic, but it can infect with high efficiency both dividing and terminally-differentiated ...Author: Matthew J During
https://www.takarabio.com/learning-centers/gene-function/viral-transduction/recombinant-virus-comparison
However, selecting the best viral gene delivery system for your experimental aim can be challenging. Use the tables below to compare the characteristics of lentivirus, retrovirus, adenovirus, and adeno-associated virus (AAV), and select the best viral transduction system for your experiment.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2570152/
Summary: The unique life cycle of adeno-associated virus (AAV) and its ability to infect both nondividing and dividing cells with persistent expression have made it an attractive vector. An additional attractive feature of the wild-type virus is the lack of apparent pathogenicity. Gene transfer ...Author: Shyam Daya, Kenneth I. Berns
https://www.cellbiolabs.com/news/adeno-associated-virus-aav-provides-advantages-gene-delivery
Adeno-Associated Virus (AAV) Provides Advantages for Gene Delivery Recombinant adeno-associated virus ( AAV ) is often the preferred method for delivering genes to target cells due to its high titer, mild immune response, ability to infect a broad range of cells, and overall safety.
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