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https://www.sciencedirect.com/science/article/pii/S1359644620300738
Zeolite A and zeolite X powders were used as porous containers with desirable surface morphologies for drug delivery applications. Zeolites cannot retain ketoprofen sodium salt, because of the repulsion of negative charges; thus, ketoprofen loading without activation treatment failed.Author: Morteza Servatan, Payam Zarrintaj, Ghader Mahmodi, Seok-Jhin Kim, Mohammad Reza Ganjali, Mohammad Re...
https://www.ncbi.nlm.nih.gov/pubmed/32062009
Feb 13, 2020 · Given their diverse structures, zeolites have attracted significant research attention for controlled and targeted drug delivery purposes. The structure of zeolites can be microporous, mesoporous or macroporous, which can be exploited to deliver a variety of therapeutic agents to the target site in a controlled manner. In this review, we introduce the different types of zeolite, and discuss the challenges and opportunities associated with their usage as drug delivery …Author: Morteza Servatan, Payam Zarrintaj, Ghader Mahmodi, Seok-Jhin Kim, Mohammad Reza Ganjali, Mohammad Re...
https://www.ncbi.nlm.nih.gov/pubmed/18085645
Drug-loaded matrices were then characterized for entrapped drug amount and thermogravimetric behavior. In both types of activated zeolites, the total amount of ketoprofen (800 mg) was encapsulated in 2 g of matrix. By using HPLC measurements, ketoprofen release studies were done at different pH conditions so as to mimick gastrointestinal fluids.Author: Maria G. Rimoli, Maria R. Rabaioli, Daniela Melisi, Annalisa Curcio, Sandro Mondello, Rosella Mirabe...
https://neuro.psychiatryonline.org/doi/full/10.1176/appi.neuropsych.12010010
Zeolites contain a network of nano-pores with diameters usually less than 20 nm. Substitution of drugs into nano-zeolites is practical and achievable. The arbitrary drug is trapped into the nano-pores of the zeolite, which can be recovered in due time. Many in-vitro and in-vivo experiments are executed on natural and artificial zeolites.Author: Ali Hassanvand, Mojtaba Hajihassani, Mohamad Abdi, Shahriar Gharibzadeh
https://www.sciencedirect.com/science/article/abs/pii/S0927776513004785
The in vitro dissolution from the drug delivery systems (DDS) was explained by the Weibull model. The DDS efficacy was evaluated using two human colorectal carcinoma cell lines, HCT-15 and RKO. Unloaded zeolites presented no toxicity to both cancer cells, while all DDS allowed an important potentiation of the 5-FU effect on the cell viability.Author: Natália Vilaça, Ricardo Amorim, Ana F. Machado, Pier Parpot, Manuel F.R. Pereira, Mariana Sardo, Joã...
https://pubs.acs.org/doi/abs/10.1021/jp3093868
The zeolites in the sodium form (NaY and NaA) were used as hosts for encapsulation of α-cyano-4-hydroxycinnamic acid (CHC). CHC, an experimental anticancer drug, was encapsulated in both zeolites by diffusion in liquid phase. These new drug delivery systems, CHC@zeolite, were characterized by spectroscopic techniques (FTIR, 1 H NMR,...Author: Ricardo Amorim, Natália Vilaça, Olga Martinho, R. M. Reis, Mariana Sardo, João Rocha, António Manuel...
https://ir.uiowa.edu/cgi/viewcontent.cgi?article=3443&context=etd
Zeolites and mesoporous silica were used as drug delivery systems for the loading and release of small drug molecules, aspirin and 5-fluorouracil. Different parameters were varied such as aluminum content in the zeolite, effect of distribution of functional groups and the method of surface modification in case of mesoporous silica.Author: Ashish Datt
https://www.mskcc.org/cancer-care/integrative-medicine/herbs/zeolite
Jun 30, 2017 · Zeolites have limited use in medicine as an external hemostatic dressing for trauma-related injuries (12), potential for controlled drug delivery, as a suspending agent, or for use in cardiopulmonary bypass and hemodialysis procedures (13) (14) (15).
https://www.researchgate.net/publication/5762405_Synthetic_zeolites_as_a_new_tool_for_drug_delivery
Synthetic zeolites as a new tool for drug delivery. Synthetic zeolites were studied in order to investigate their ability to encapsulate and to release drugs. In particular, a zeolite X and a zeolitic product obtained from a cocrystallization of zeolite X and zeolite A were examined.
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