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https://www.researchgate.net/publication/233771200_Well-Defined_Degradable_Brush_Polymer-Drug_Conjugates_for_Sustained_Delivery_of_Paclitaxel
Request PDF Well-Defined Degradable Brush Polymer-Drug Conjugates for Sustained Delivery of Paclitaxel To achieve a conjugated drug delivery system with high drug loading but minimal long-term ...
https://www.ncbi.nlm.nih.gov/pubmed/23181264
Mar 04, 2013 · Well-defined degradable brush polymer-drug conjugates for sustained delivery of Paclitaxel. Yu Y(1), Chen CK, Law WC, Mok J, Zou J, Prasad PN, Cheng C. Author information: (1)Department of Chemical and Biological Engineering, Photonics and Biophotonics, The State University of New York at Buffalo , Buffalo, New York 14260, USA.Author: Yun Yu, Chih-Kuang Chen, Wing-Cheung Law, Jorge Mok, Jiong Zou, Paras N. Prasad, Chong Cheng
https://www.sciencedirect.com/science/article/pii/S0168365914006385
Well-defined polymer-drug conjugate engineered with redox and pH-sensitive release mechanism for efficient delivery of paclitaxel. ... J. Zou, P.N. Prasad, C. ChengWell-defined degradable brush polymer-drug conjugates for sustained delivery of paclitaxel.Author: Shixian Lv, Zhaohui Tang, Dawei Zhang, Wantong Song, Mingqiang Li, Jian Lin, Huaiyu Liu, Xuesi Chen
https://pubs.rsc.org/en/content/articlelanding/2015/py/c4py01194e#!
To achieve high precision and efficacy in disease treatment, biodegradability and environmental responsivity are highly desired in drug delivery systems. Having a polylactide (PLA)-based biodegradable scaffold conjugated with doxorubicin (DOX) moieties via pH-responsive linkages, a brush polymer–drug …
https://www.researchgate.net/publication/257299828_Hydrolytically_degradable_polymer_micelles_for_drug_delivery_A_SAXSSANS_kinetic_study
Hydrolytically degradable polymer micelles for drug delivery: A SAXS/SANS kinetic study Article in Biomacromolecules 14(11) · October 2013 with 321 Reads How we measure 'reads'
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846103/
Drug Release Kinetics and Transport Mechanisms of Non-degradable and Degradable Polymeric Delivery Systems. Yao Fu 1 and Weiyuan John Kao, PhD †, 1, 2, 3 ... As shown in Table 1, drug release from PDMS-based delivery devices can be sustained to over a month.
https://www.sciencedirect.com/science/article/pii/S0168365908000254
A review of stimuli-responsive nanocarriers for drug and gene delivery. ... When polymer–drug conjugates are administered, ... the availability of well-defined water-soluble polymers with uniform dispersities and that are nontoxic and biocompatible is rather limited. Dendritic polymers are promising polymeric drug carriers due to their well ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881612/
May 23, 2016 · 2. Structure and Activity Relationships. As for prodrug strategy, understanding the structure and activity relationship is the first step. Pioneer work showed that the central part of paclitaxel is rigid to a change in structure, while its side chain tail can be flexible [].In the central part of paclitaxel, the 1-OH and 2-benzoyloxy are important to paclitaxel’s anti-cancer activity [].Author: Ziyuan Meng, Quanxia Lv, Jun Lu, Houzong Yao, Xiaoqing Lv, Feng Jiang, Aiping Lu, Ge Zhang
http://www.authorstream.com/Presentation/vamsikrishnareddy-255095-polymers-drug-delivery-system-used-systems-science-technology-ppt-powerpoint/
Oct 15, 2009 · polymers in drug delivery system. vamsikrishnareddy. Download ... POLYMERS USED IN DRUG DELIVERY SYSTEM SUBMITTED BY B. Vamsikrishna Reddy M.Pharm first year, Pharmaceutics, MCOPS,Manipal. ... Ideal candidates among model hyperbranched polymers because of their well-defined structure and high density of functional groups.
https://www.sciencedirect.com/science/article/pii/S0014305718303860
Herein, we have reported an in-situ polymerization approach for synthesis of cRGD-end-functionalized well-defined polymers as potential building blocks of targeted drug delivery systems. A new cRGD peptide functionalized RAFT agent was synthesized as confirmed by MALDI-TOF and 1 H NMR spectroscopy. The ability of this RAFT agent to control ...Author: Hajeeth Thankappan, Aykut Zelcak, Damla Taykoz, Volga Bulmus
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