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https://www.pharmatutor.org/articles/wafers-technology-newer-approacah-smart-drug-dilevery-system
The lyophilized wafer developed throughout this review is an effective and versatile drug delivery system for oramucosal application. This has been established from the extensive physicochemical and physic mechanical profiling conducted.
https://www.bcm.edu/news/eye/nanowafer-more-effective-than-eye-drops
Feb 04, 2015 · In their latest study published in ACS Nano, researchers found that in mice, the nanowafer drug delivery system was more effective in treating corneal neovascularization, which results in severe corneal clouding and blood vessel ingrowth, than a topical eye drop therapy. “Eye drops are very inefficient because they are diluted out by the ...
https://www.sciencedirect.com/science/article/pii/S2090123219300888
A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates ... S. Barua, H. Kim, K. Jo, C.W. Seo, T.J. Park, K.B. Lee, et al.Drug delivery techniques for buccal route: formulation strategies and recent advances in dosage form design. J Pharm Investig, 46 (2016), pp. 593-613.Author: Juliana Souza Ribeiro Costa, Karen de Oliveira Cruvinel, Laura Oliveira-Nascimento
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6526303/
A mini-review on drug delivery through wafer technology: Formulation and manufacturing of buccal and oral lyophilizates. Juliana Souza Ribeiro Costa, a, b Karen de Oliveira Cruvinel, a …Author: Juliana Souza Ribeiro Costa, Karen de Oliveira Cruvinel, Laura Oliveira-Nascimento
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4483039/
Mar 05, 2015 · Polymeric drug delivery systems have been developed to allow controlled local release of biologically active substances for a variety of conditions. Their primary advantages relate to their ability to achieve high local concentrations of active agents while limiting or eliminating systemic toxicities.Author: Scott D. Wait, Roshan S. Prabhu, Stuart H. Burri, Tyler G. Atkins, Anthony L. Asher
http://ijpda.com/admin/uploads/tJXjW8.pdf
In fast dissolving drug delivery sys-tems, Oral flash release wafer drug delivery system is an alternative to tablets, capsules, and syrups for the patients who feel difficult to swallow the traditional oral solid dosage forms such as paediatric and geriatric patients. For rapid drug release causes its direct systemic circulation in the oral ...File Size: 469KB
https://www.hopkinsmedicine.org/neurology_neurosurgery/centers_clinics/brain_tumor/research/gliadel-wafer.html
The GLIADEL® wafer is a biodegradable polymer loaded with the chemotherapeutic agent BCNU used for the treatment of recurrent gliomas. It was approved by the FDA in 1995. After surgical removal of the brain tumor, GLIADEL® wafers are soaked with a chemotherapy drug (BCNU) and are implanted in the space where the tumor was.
http://chemocare.com/chemotherapy/drug-info/gliadel-wafer.aspx
How Carmustine Wafer Is Given: Gliadel® wafer is a form of the medication carmustine that can be placed and left in the cavity after surgical removal of a brain tumor. The carmustine wafer allows for delivery of the drug directly to the site of the brain tumor.
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0111547
Schematic representation of the concept of combining hydrogel-forming microneedles prepared from super swelling polymers and lyophilised wafer-type drug reservoirs for enhanced transdermal delivery of proteins and high dose low potency drug substances.
https://www.aiche.org/chenected/2014/02/evolution-drug-delivery
Feb 19, 2014 · Recently nanodiamonds have stolen the limelight with uses ranging from drug delivery of chemotherapy drugs for treating chemotherapy resistant cancers to nanodiamond-silk hybrids for fluorescent bioimaging and drug delivery. Wafers and micro-needles. The Gliadel Wafer, a PixarBio product has received worldwide acclamation.
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