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https://www.researchgate.net/publication/305747489_Virus-like_particles_as_drug_delivery_vectors
Viral capsid proteins can form hollow spherical structures, as caged platforms, with monolayer walls called "virus-like particles (VLPs)" that have icosahedral symmetry, and as a relatively new...
https://en.wikipedia.org/wiki/Viral_Like_Particle
Virus-like particles (VLPs) are molecules that closely resemble viruses, but are non-infectious because they contain no viral genetic material.They can be naturally occurring or synthesized through the individual expression of viral structural proteins, which can then self assemble into the virus-like …
https://www.youtube.com/watch?v=ylDRjNlkB9I
May 19, 2014 · This three part, stop motion video addresses VLP capsid assembly, drug loading, and VLP drug delivery. Music: Teardrop by Massive AttackAuthor: Kimberly Legaux
https://indianexpress.com/article/technology/science/creating-virus-like-particles-for-drug-delivery/
More recently, we used our understanding of the structure of the virus to create new virus-like nano-sized particles (VLPs) that can be used as carriers in a variety of applications, including drug delivery, vaccines, imaging and developing diagnostic kits. Viruses are at the cusp of living organisms and inanimate matter.
https://www.pnas.org/content/108/41/16998
Oct 11, 2011 · Retroviral vectors are often used for gene delivery; however, integration of the genome of retroviral vector into the host genome can have serious consequences. Here we describe a safe alternative in which virus-like particles (VLPs), derived from …
https://www.medgadget.com/2015/09/engineered-smart-particles-drug-delivery.html
Engineered Virus-Like Particles for Drug Delivery ... and more specifically tried to reprogram the HepB virus to act as a drug delivery capsule, but it had proven extremely difficult to do so ...
http://www.eurekaselect.com/openurl/content.php?genre=article&issn=1389-2010&volume=6&issue=1&spage=49
The drug delivery system described here is based on a virus like particle consisting of the recombinant expressed major capsid protein of Polyomavirus, VP1. Polyoma, a murine virus belonging to the Papovaviridae, forms a non-enveloped icosahedral capsid.
https://www.researchgate.net/publication/8005185_Recombinant_Virus_Like_Particles_as_Drug_Delivery_System
The drug delivery system described here is based on a virus like particle consisting of the recombinant expressed major capsid protein of Polyomavirus, VP1.
https://www.youtube.com/watch?v=mhriuXRQYak
Oct 08, 2012 · Animation of the process of creating a virus like particle with a specific drug, ignoring healthy (orange) cells and acting on sick (grey) cells. Animation is made entirely with Blender 2.63. The ...Author: surfrender
https://techtransfer.cancer.gov/availabletechnologies/e-264-2011
The present invention describes novel virus-like particles (VLPs) that are capable of binding to and replicating within a target mammalian cell, including human cells. The claimed VLPs are safer than viral delivery because they are incapable of re-infecting target cells. The National Cancer Institute's Protein Expression Laboratory seeks parties interested in licensing
https://www.slideshare.net/MohammadAbrarGayath/virus-like-particles
Jan 16, 2017 · Virus Like Particles 1. VIRUS LIKE PARTICLES Abrar Gayas VB/2011/1075 3rd YEAR 2. WHAT? VLPs are formed by structural viral proteins which have an inherent property for self-assembly, and mimic the morphology of the pathogen. In contrast to live viruses, VLPs are non- infective and non-replicating, since they are essentially devoid of infectious genetic material.
https://www.mdpi.com/2079-4991/8/12/1007/htm
We therefore set out to evaluate a panel of morphologically distinct protein nanoparticles for their potential as CED drug delivery vehicles for glioblastoma treatment. The panel consisted of three different virus-like particles (VLPs), MS2 spheres, tobacco mosaic virus (TMV) disks and nanophage filamentous rods modified with DOX.
https://www.acib.at/virus-like-particle/
Apr 26, 2017 · Virus like particles are important tools in the medical field for vaccination or drug delivery systems. They mimic the outside structure of a virus but cannot reproduce themselves anymore. The purification thereof is still a challenge, but some techniques are published already.
https://www.semanticscholar.org/paper/Virus-like-particles-as-drug-delivery-vectors.-Zdanowicz-Chroboczek/6f00c9cbc7bedb5037cea51d55be3b9c1b09f466/figure/0
After Smith et al., 2013. Right panel – influenza VLPs produced in a baculovirus system with the sequences of the genes for HA, NA, and M1 of the 1918 pandemic virus. After Perrone et al., 2009. - "Virus-like particles as drug delivery vectors."
https://www.pulsus.com/scholarly-articles/viral-nanoparticles-a-drug-delivery-platform.pdf
Viral nanoparticles: A drug delivery platform Alaa AA Aljabali PhD O ver the past decade, there has been an increased interest in the biomaterials field for various applications. The development of cancer treatment methods (chemotherapy, radiation and hormone therapy) has saved millions of lives. However, the problem with this treatment remains
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