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https://www.ondrugdelivery.com/simplified-drug-vaccine-delivery-using-microns-microneedle-patch/
Citation: McAllister DV, Henry S, Prausnitz M, “Simplified Drug and Vaccine Delivery Using Micron’s Microneedle Patch”. ONdrugDelivery Magazine, Issue 84 (Mar 2018), pp 20-23.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465129/
Vaccine drug delivery systems are gaining popularity these days due to the benefits they offer. Vaccine drug delivery systems are now being proven to be patient friendly as they avoid the need to administer booster doses and provide a long term therapy in small doses.
https://www.hindawi.com/journals/jir/2019/8303648/
Intradermal immunization for vaccine delivery is an upcoming strategy showing significant advantages over conventional vaccination routes. In particular, in the last few years, intradermal vaccination has gained momentum as an alternative and more effective vaccine delivery route, both from a scientific and a commercial point of view (Table 3).Author: E. Criscuolo, V. Caputo, V. Caputo, R. A. Diotti, R. A. Diotti, G. A. Sautto, G. A. Kirchenbaum, N. ...
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in …
https://www.longdom.org/proceedings/vaccine-drug-delivery-systems-30354.html
Carrier systems such as liposomes, microspheres, nanoparticles, dendrimers, micellar systems, ISCOMs, plant-derived viruses are being investigated and developed as vaccine delivery systems. Amongst others, development of “needle free technologies”, to help administration of vaccines through different routes into the human body, is generating worldwide interest.
https://www.slideshare.net/KusumaLathaBeera1/vaccine-drug-delivery-systems
Nov 13, 2018 · NEEDLE FREE VACCINE DELIVERY: The development of needle‐free delivery systems for vaccines has been named one of the Grand - Challenges in Global Health. Needles are associated with an increased risk of infect ion, especially in developing countries, where there are problems with needles being reused and issue s with waste management and disposal.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794664/
Oct 14, 2019 · Compared with oral and hypodermic administrations, transdermal drug delivery can overcome the problem of absorption and degradation of drugs occurring in the gastrointestinal tract or the liver; it is convenient, inexpensive, noninvasive, painless, and self-administrated; as well as it can provide sustained release of drugs to improve patient compliance. 2,8,9 However, the stratum corneum imposes significant restrictions on the successful delivery of drugs…
https://www.ondrugdelivery.com/imv-development-of-dpx-covid-19-vaccine-its-ongoing-business-and-clinical-operations/
Canadian biotech company IMV has made impressively rapid, solid progress on the development of a vaccine candidate against the novel coronavirus, using its lipid-based vaccine delivery platform, DPX. New developments in just two weeks include, include: initiation of peptide candidate manufacturing, cGMP scale-up plans, preclinical models/assays; and Phase I clinical trial design completed ...
https://www.fda.gov/vaccines-blood-biologics/vaccines
Vaccines approved for marketing may also be required to undergo additional studies to further evaluate the vaccine and often to address specific questions about the vaccine's safety, effectiveness ...
https://en.wikipedia.org/wiki/Jet_injector
August 14, 2014: The U.S. Food and Drug Administration (FDA) approved the use of the PharmaJet Stratis 0.5ml Needle-free Jet Injector for delivery of one particular flu vaccine (AFLURIA® by bioCSL Inc.) in people 18 through 64 years of age.
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