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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438887/
The majority of responsive polymers for drug delivery can be broadly categorized as hydrogels, micelles, polyplexes, or polymer-drug conjugates, which are covered in more detail below. Hydrogels are hydrophilic (co)polymeric networks capable of imbibing large …Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
https://www.mddionline.com/polymers-controlled-drug-delivery
Work with biodegradable polymers has also yielded polyorthoesters that are pH sensitive and that will degrade more quickly in acidic environments. 3 Such polymers have been studied as the central core of a drug delivery system in which the polymer-insulin matrix is surrounded by a membrane containing grafted glucose oxidase, which provides the reaction substrate and the change in pH necessary to enhance biodegradation and subsequent insulin delivery.
https://www.sciencedirect.com/science/article/pii/S1367593100002271
Advances in polymer science have led to the development of several novel drug-delivery sytems. A proper consideration of surface and bulk properties can aid in the designing of polymers for various drug-delivery applications. Biodegradable polymers find widespread use in drug delivery as they can be degraded to non-toxic monomers inside the body.Author: Omathanu Pillai, Ramesh Panchagnula
https://pubs.acs.org/doi/10.1021/jp994274o
The mass transfer through the membranes has been successfully treated using a simple diffusion model (D ∼ 5 × 10-9 cm 2 s-1) and discussed with regards to the polymer's structure and potential drug delivery device applications. Hydrazine (0.1 M) and alkaline medium (pH 12) have been used as chemical triggers for ATP release from PPy/ATP membranes.Author: Jean-Michel Pernaut, John R. Reynolds
https://pubsapp.acs.org/email/cen/html041805042508.html
MediVas' polymers can also be used to produce PEA nano- and microparticles for tissue-targeted drug delivery and for the delivery of biologics such as antisense molecules--single- or double-stranded RNA or DNA--into cells without the use of viral or other vectors or adjuvants.
https://file.scirp.org/pdf/JBM_2016011414462012.pdf
Polymers are being used extensively in drug delivery due to their surface and bulk properties. They are being used in drug formulations and in drug delivery devices. These drug delivery devic- es may be in the form of implants for controlled drug delivery.
https://www.researchgate.net/publication/307866830_Polymers_in_Drug_Delivery_Technology_Types_of_Polymers_and_Applications
of low molecular weight drugs, and has a potential of targeted drug delivery. such as the naturals polymers are most abundant and biodegradable but are difficult to reproduce and purify. polymers have high immunogenicity, which prevent their long term usage. sugary after they release the drug …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3912992/
Introduction. Drug delivery systems (DDSs) are important for effective, safe, and convenient administration of drugs. pH- and ion-responsive polymers have been widely employed in DDS for site-specific drug release due to their abilities to exploit specific pH- or ion-gradients in the human body.Author: Takayuki Yoshida, Tsz Chung Lai, Glen S Kwon, Kazuhiro Sako
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/polymer-nanoparticles-for-smart-drug-delivery
The application of molecular imprinting enables the design of new systems and also in polymer based device fabrications. The advances in the preparation of molecular imprinting as spherical uniform particles and scaffolds can increase the field application potentiality of several polymers in drug delivery system. Moreover, these imprinted delivery systems have not yet touched in clinical therapeutics.Author: Devasier Bennet, Sanghyo Kim
https://www.annualreviews.org/doi/abs/10.1146/annurev-chembioeng-073009-100847
Polymers have played an integral role in the advancement of drug delivery technology by providing controlled release of therapeutic agents in constant doses over long periods, cyclic dosage, and tunable release of both hydrophilic and hydrophobic drugs. From early beginnings using off-the-shelf materials, the field has grown tremendously, driven in part by the innovations of chemical engineers ...Author: William B. Liechty, David R. Kryscio, Brandon V. Slaughter, Nicholas A. Peppas
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