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https://www.ncbi.nlm.nih.gov/pubmed/18204175
Novel approaches to enhance pulmonary delivery of proteins and peptides. ... In the last two decades, large efforts have been made to develop safe methods for the delivery of proteins and peptides via the lungs into blood circulation for treatment of systemic diseases. For this purpose, a number of biophysical and physiological parameters have ...Author: Scheuch G, Siekmeier R
http://www.jpp.krakow.pl/journal/archive/11_07_s5/pdf/615_11_07_s5_article.pdf
G. SCHEUCH1, R. SIEKMEIER2 NOVEL APPROACHES TO ENHANCE PULMONARY DELIVERY OF PROTEINS AND PEPTIDES 1Activaero, Gemünden/Wohra, Germany; 2Federal Institute for Drugs and Medical Devices (BfArM), Bonn (Germany) In the last two decades, lar ge efforts have been made to develop safe methods for the
https://www.sciencedirect.com/science/article/pii/S0167779909001437
Another promising approach to enhance the stability of therapeutic peptides and proteins is their encapsulation into a micro- or nanoparticle, with the aim of protecting the drug from the hostile environment in the body .At their target location, biodrugs typically are released from the particle by diffusion, swelling, erosion or degradation .Such nano-enabled drug delivery systems have ...Author: Zuzana Antosova, Martina Mackova, Vladimir Kral, Tomas Macek
https://www.sciencedirect.com/science/article/pii/S0169409X18300085
The impact of proteins and peptides on the treatment of various conditions including ocular diseases over the past few decades has been advanced by substantial breakthroughs in structural biochemistry, genetic engineering, formulation and delivery approaches.Author: Abhirup Mandal, Dhananjay Pal, Vibhuti Agrahari, Hoang My Trinh, Mary Joseph, Ashim K. Mitra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Pulmonary drug delivery strategies: A concise, systematic review. J. S. Patil and S. Sarasija 1 ... such as proteins and peptides, because mechanical high- energy input is avoided in this process. More importantly, ... Siekmeier R. Novel approaches to enhance pulmonary delivery of proteins and peptide. J Physio Pharmacol. 2007; 58:615–25.
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(09)00143-7
Sep 21, 2009 · Varied therapeutic peptides and proteins represent a rapidly growing part of marketed drugs and have an undisputed place alongside other established therapies. Nevertheless, such biodrugs have several drawbacks that hinder their therapeutic application. ... Novel approaches to enhance pulmonary delivery of proteins and peptides. J. Physiol ...Author: Zuzana Antosova, Martina Mackova, Vladimir Kral, Tomas Macek
https://www.researchgate.net/publication/285008363_Novel_approaches_to_nasal_delivery_of_peptides_and_proteins
Download Citation Novel approaches to nasal delivery of peptides and proteins Oral administration of peptides and proteins is severely limited by degradation in the gastrointestinal tract and ...
https://www.researchgate.net/publication/328265448_PROTEIN_AND_PEPTIDE_DRUG_DELIVERY_SYSTEM
Protein and Peptide drug delivery system are the Novel drug Delivery System. Proteins and peptides are the most abundant components of biological cells.
http://pharmrev.aspetjournals.org/content/67/3/541
Jul 01, 2015 · Peptides have long been recognized as a promising group of therapeutic substances to treat various diseases. Delivery systems for peptides have been under development since the discovery of insulin for the treatment of diabetes. The challenge of using peptides as drugs arises from their poor bioavailability resulting from the low permeability of biological membranes and their instability ...Author: Miia Kovalainen, Juha Mönkäre, Joakim Riikonen, Ullamari Pesonen, Maria Vlasova, Jarno Salonen, Vesa...
https://www.powershow.com/view/3e3dd-NzYwZ/NOVEL_APPROACHES_TO_ENHANCE_THE_PULMONARY_DELIVERY_OF_BIOTHERAPEUTICS_powerpoint_ppt_presentation?varnishcache=1
NOVEL APPROACHES TO ENHANCE THE PULMONARY DELIVERY OF BIOTHERAPEUTICS - PowerPoint PPT Presentation ... Title: NOVEL APPROACHES TO ENHANCE THE PULMONARY DELIVERY OF BIOTHERAPEUTICS 1 ... It is possible to deliver proteins, peptides and vaccines efficiently with the AKITA technology. 35
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