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https://www.cambridge.org/core/journals/international-journal-of-technology-assessment-in-health-care/article/novel-approaches-to-controlledrelease-antigen-delivery/998C1FDE6A12793EBE30EC2942CA5A06
Oct 14, 2009 · Novel Approaches to Controlled-Release Antigen Delivery. Two strategies for vaccine-delivery systems, both relying on concepts of controlled-release technology, are described in this review. The first strategy involves using biodegradable polymer microspheres for parenteral and oral delivery of antigens.Author: Smadar Cohen, Maria J. Alonso, Robert Langer
https://www.ncbi.nlm.nih.gov/pubmed/8157444
Novel approaches to controlled-release antigen delivery. Cohen S(1), Alonso MJ, Langer R. Author information: (1)Ben Gurion University of the Negev, Israel. Two strategies for vaccine-delivery systems, both relying on concepts of controlled-release technology, are described in this review.Author: Smadar Cohen, Maria J. Alonso, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6468175/
Apr 08, 2019 · These particles are able to either entrap or adsorb antigen for delivery to specific cells or allow for sustained antigen release over time because of their slow biodegradation rate 80, 81.Author: J. Wallis, D. P. Shenton, R. C. Carlisle
https://link.springer.com/10.1023/B:PHAM.0000041443.17935.33
Sep 01, 2004 · Alternatively, novel approaches to delivery, including mucosal administration, may be used to improve compliance for existing vaccines. Of particular interest for safer mass immunization campaigns are needle-free delivery devices, which would avoid problems due to needle re-use in many parts of the world and would avoid needle-stick injuries.Author: Derek T. O'Hagan, Rino Rappuoli
https://www.sciencedirect.com/science/article/pii/S0014305719305920
Polyanhydrides have been investigated for controlled release of drugs treating eye disorders, and also for delivery of antineoplastic agents , local anesthetics, anticoagulants neuroactive drugs , antibiotics, vaccines and proteins .Author: Shiv Kumar Prajapati, Ankit Jain, Aakanchha Jain, Sourabh Jain
https://innovareacademics.in/journal/ijpps/Vol4Issue3/3529.pdf
The drug release pattern from these systems depends on a carrier which is used in the formation of multiparticulates and the amount of drug enclosed in them. Thus multiparticulate drug delivery systems provide incredible opportunities for designing novel controlled and delayed release oral formulations.
https://www.sciencedirect.com/book/9780124166035/novel-approaches-and-strategies-for-biologics-vaccines-and-cancer-therapies
Novel Approaches and Strategies for Biologics, Vaccines and Cancer Therapies takes a look at the current strategies, successes and challenges involved with the development of novel formulations of biologics, vaccines and cancer therapy. This thorough reference on the latest trends in the development of diverse modalities will appeal to a broad ...
https://www.sciencedirect.com/science/article/pii/S093964110000062X
Controlled release of a micromolecule and proteins from the in situ formed PLGA microspheres produced from a novel coacervation process is described here. The in vitro drug release was enhanced with decrease in the PEG 400 concentration and increase in the drug and mannitol concentration.Author: Jain Ra, Rhodes Ct, Railkar Am, Malick Aw, Shah Nh
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6108334/
Aug 20, 2018 · Novel approaches to extended-release drug delivery A number of novel NP formulations for extended drug release have been developed in recent years. For instance, PLGA polymers have been shown to attain 82% of the cumulative release of dexamethasone in 17 days. 130 Clinically, cancer patients undergoing chemotherapy are often given dexamethasone to counteract the adverse side effects of their antitumor treatment.Author: Regina-Veronicka Kalaydina, Komal Bajwa, Bessi Qorri, Alexandria Decarlo, Myron R Szewczuk
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