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https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
Aug 01, 2018 · In addition to assessing safety, feasibility, and efficacy of ultrasound-triggered targeted drug delivery, part I was also designed to capture thermometry data to help predict ultrasound parameters for part II of the study.Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...
https://www.sciencedirect.com/science/article/pii/S0169409X13002962
For ultrasound-triggered drug delivery, the main properties that are necessary to achieve a significant increase in TI are (1) stable encapsulation of the drug compound prior to application of ultrasound, (2) release of the drug by ultrasound stimulation and (3) the ability to image the carrier and monitor delivery of the drug cargo.Author: Shashank R. Sirsi, Mark A. Borden
https://www.sciencedirect.com/science/article/pii/S0168365916308070
Nov 10, 2016 · Ultrasound-triggered drug delivery is now becoming a mature technology with first patients enrolling in clinical trials. Having a clear overview of the field is complicated as it mixes ultrasound physics and biological effects, particle formulation, and pharmacokinetics and biodistribution.Author: Tanguy Boissenot, Alexandre Bordat, Elias Fattal, Nicolas Tsapis
https://link.springer.com/article/10.1007/s12274-018-2188-4
Sep 06, 2018 · A proof-of-principle demonstration of the suppression of inflammation activation of macrophage upon ultrasound-triggered release of TA was also illustrated. We anticipate that this novel hydrogel-based drug delivery system can be used for the treatment of inflammatory diseases on load-bearing tissues, such as muscle and cartilage.Author: Wenxu Sun, Heting Jiang, Xin Wu, Zhengyu Xu, Chen Yao, Juan Wang, Meng Qin, Qing Jiang, Wei Wang, Do...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4041842/
Jun 15, 2014 · For ultrasound-triggered drug delivery, the main properties that are necessary to achieve a significant increase in TI are (1) stable encapsulation of the drug compound prior to application of ultrasound, (2) release of the drug by ultrasound stimulation and (3) the ability to image the carrier and monitor delivery of the drug cargo.Author: Shashank R. Sirsi, Mark A. Borden
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4761943/
However, it is still difficult to achieve local drug delivery in a spatio-temporally controllable manner under real-time image guidance. Here, we introduce an ultrasound (US) triggered image-guided drug delivery approach to inhibit vascular reconstruction via paclitaxel (PTX)-loaded microbubbles (PLM) in a rabbit iliac balloon injury model.Author: Xu Zhu, Jun Guo, Cancan He, Huaxiao Geng, Gengsheng Yu, Jinqing Li, Hairong Zheng, Xiaojuan Ji, Fei ...
https://www.nature.com/articles/natrevmats201720
May 09, 2017 · Drug delivery systems that are externally triggered to release drugs and/or target tissues hold considerable promise for improving the treatment of …Author: Yanfei Wang, Daniel S. Kohane
https://www.nature.com/articles/srep21683
Feb 22, 2016 · Here, we introduce an ultrasound (US) triggered image-guided drug delivery approach to inhibit vascular reconstruction via paclitaxel (PTX)-loaded microbubbles (PLM) in a rabbit iliac balloon ...Author: Xu Zhu, Jun Guo, Cancan He, Huaxiao Geng, Gengsheng Yu, Jinqing Li, Hairong Zheng, Xiaojuan Ji, Fei ...
https://link.springer.com/article/10.1007%2Fs13346-017-0448-6
Dec 04, 2017 · Ultrasound is a unique and theranostic modality that can be employed to track drug carriers, trigger drug release, and improve drug deposition with high precision [].In the pharmaceutical industries, the application of ultrasound to promote chemical processes is known as sonochemistry.Author: Ankit Jain, Ankita Tiwari, Amit Verma, Sanjay K. Jain
https://www.future-science.com/doi/10.4155/tde-2017-0100
Dec 08, 2017 · ultrasound-triggered drug delivery Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript.Author: Kathleen Cullion, Alina Y Rwei, Daniel S Kohane
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