Ultrasound Targeted Drug Delivery

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Ultrasonic Drug Delivery – A General Review

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
    Gene delivery is a topic of intense interest in targeted drug delivery [43–49]. The use of ultrasound in gene delivery has exceptional potential because the beam can be focused on a particular tissue. The trick, as always, is to release the genetic material only at the targeted site.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples

Safety and feasibility of ultrasound-triggered targeted ...

    https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(18)30332-2/fulltext
    Aug 01, 2018 · To our knowledge, our study was the first to attempt non-invasive ultrasound-mediated targeted hyperthermia for triggered drug release and enhanced drug delivery in a clinical setting. Apart from the existing risks associated with general anaesthesia, the overall intervention posed no additional safety concerns to the patient other than those typically associated with chemotherapy alone.Author: Paul C Lyon, Paul C Lyon, Paul C Lyon, Michael D Gray, Christophoros Mannaris, Lisa K Folkes, Michae...

Targeted drug delivery across the blood–brain barrier ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140134/
    Dec 01, 2010 · Ultrasound targeted drug delivery to the brain across the BBB is a novel strategy that has advantageous characteristics over other techniques. Successful development and translation of the technology will have a significant impact on the treatment of various diseases in the CNS.Author: Cheri X Deng

Ultrasound to enhance cancer drug delivery: Sound waves ...

    https://www.sciencedaily.com/releases/2018/03/180320084420.htm
    Mar 20, 2018 · Ultrasound to enhance cancer drug delivery. Sound waves drive drug therapies to cancer cells; minimize toxicity. FULL STORY. For decades, ultrasound has been used to image organs such as the heart and kidneys, check blood flow, monitor the development of fetuses, reduce pain and even break up kidney stones.

Ultrasound-enhanced Vascular Permeability for Targeted ...

    https://www.nature.com/naturecareers/job/ultrasoundenhanced-vascular-permeability-for-targeted-drug-delivery-concordia-university-721105
    Ultrasound-enhanced Vascular Permeability for Targeted Drug Delivery Concordia University Montreal, Quebec, CanadaWork Location: Quebec

Ultrasound and Microbubble Guided Drug Delivery ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4084724/
    Temperature sensitive liposomes can stably carry drugs in the bloodstream and are triggered to release the drugs in the targeted region when the local temperature is increased by ultrasound hyperthermia. This combination can significantly enhance drug delivery compared to using ultrasound …Author: Tzu-Yin Wang, Katheryne E. Wilson, Steven Machtaler, Jurgen K. Willmann

Ultrasound-sensitive nanoparticle aggregates for targeted ...

    https://www.sciencedirect.com/science/article/pii/S0142961217303976
    Here we describe injectable, ultrasound (US)-responsive, nanoparticle aggregates (NPAs) that disintegrate into slow-release, nanoscale, drug delivery systems, which can be targeted to selective sites by applying low-energy US locally.Author: Anne-Laure Papa, Netanel Korin, Mathumai Kanapathipillai, Akiko Mammoto, Tadanori Mammoto, Amanda Ji...

DNA-Conjugated Gold Nanoparticles for Ultrasound Targeted ...

    https://www.researchgate.net/publication/261118354_DNA-Conjugated_Gold_Nanoparticles_for_Ultrasound_Targeted_Drug_Delivery
    DNA-Conjugated Gold Nanoparticles for Ultrasound Targeted Drug Delivery. A novel platform based on gold nanoparticles (Au NPs) coupled with double-stranded DNA sequences and aptamers (referred to as ds(sgc8c)-Au NPs) was developed for ultrasoundcontrolled targeted drug delivery.

Drug-Loaded Perfluorocarbon Nanodroplets for Ultrasound ...

    https://www.ncbi.nlm.nih.gov/pubmed/26486341
    The interaction of nanoparticles with directed energy is a novel application in targeted drug delivery. This chapter focuses on perfluorocarbon nanoemulsions, whose action in drug delivery depends on the ultrasound-triggered phase shift from liquid to gaseous state.Author: Natalya Rapoport

Role of magnetic nanoparticles in targeted drug delivery ...

    https://www.researchgate.net/publication/309103508_Role_of_magnetic_nanoparticles_in_targeted_drug_delivery_for_central_nervous_system
    Role of magnetic nanoparticles in targeted drug delivery for central nervous system ... of progress in guiding and monitoring ultrasound energy, novel drug classes becoming available, the ...

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