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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3436072/
Jun 30, 2011 · From these beginnings, research on low-frequency ultrasound-mediated transdermal drug delivery has exploded, with dozens of different groups working on applications of this technology (see Table 2). All types of permeants, from small hydrophobic compounds, such as salicylic acid, to highly hydrophilic compounds, such as vasopressin, to proteins ...Author: Baris E. Polat, Douglas Hart, Robert Langer, Daniel Blankschtein
https://www.sciencedirect.com/science/article/pii/S0169409X14000088
Transdermal drug delivery offers an attractive alternative to the conventional drug delivery methods of oral administration and injections. However, the stratum corneum serves as a barrier that limits the penetration of substances to the skin.Author: Aharon Azagury, Luai Khoury, Giora Enden, Joseph Kost
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676802/
Ultrasound enhanced transdermal drug delivery offers advantages over traditional drug delivery methods which are often invasive and painful. A broad review of the transdermal ultrasound drug delivery literature has shown that this technology offers promising potential for noninvasive drug administration.Author: Nadine Barrie Smith
https://www.sciencedirect.com/science/article/pii/S0168365911000125
Ultrasound-mediated transdermal drug delivery: Mechanisms, scope, and emerging trends ... Abstract. The use of ultrasound for the delivery of drugs to, or through, the skin is commonly known as sonophoresis or phonophoresis. The use of therapeutic and high frequencies of ultrasound (≥ 0.7 MHz) for sonophoresis (HFS) dates back to as early as ...Author: Baris E. Polat, Douglas Hart, Robert Langer, Daniel Blankschtein
http://science.sciencemag.org/content/269/5225/850
Aug 11, 1995 · Transdermal drug delivery offers a potential method of drug administration. However, its application has been limited to a few low molecular weight compounds because of the extremely low permeability of human skin. Low-frequency ultrasound was shown to increase the permeability of human skin to many drugs, including high molecular weight proteins, by several orders of magnitude, thus …
https://www.researchgate.net/publication/331041664_Advances_in_Ultrasound_Mediated_Transdermal_Drug_Delivery
The observations demonstrated that transdermal ultrasound-mediated drug delivery is an effective method by which to control TB, particularly when compared with traditional oral anti-TB therapy and ...
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