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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
1. Mechanisms of Ultrasonic-Enhanced Drug Delivery. Ultrasound (US) has been employed to enhance the delivery and activity of drugs for the past two decades. In the past 6 years, however, research in US-activated drug delivery has blossomed with the introduction of gas bubbles.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
http://news.mit.edu/2015/ultrasound-drug-delivery-inflammatory-bowel-disease-1021
Oct 21, 2015 · Using ultrasound waves, researchers from MIT and Massachusetts General Hospital have found a way to enable ultra-rapid delivery of drugs to the gastrointestinal tract. This approach could make it easier to deliver drugs to patients suffering from GI disorders such as inflammatory bowel disease, ulcerative colitis, and Crohn’s disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2676802/
Ultrasound enhanced transdermal drug delivery offers advantages over traditional drug delivery methods which are often invasive and painful. A broad review of the transdermal ultrasound drug delivery literature has shown that this technology offers promising potential for noninvasive drug administration.Author: Nadine Barrie Smith
https://hms.harvard.edu/news/ultrasound-drug-delivery
Oct 21, 2015 · Enhanced delivery. Langer began exploring the possibility of using ultrasound to enhance drug delivery 30 years ago. In 1995, he and Blankschtein reported in Science that ultrasound could enable delivery of drugs through the skin, but until now, it had not been explored in the GI tract.
https://stm.sciencemag.org/content/7/310/310ra168.full
Oct 21, 2015 · Ultrasound-mediated drug delivery could be used for other drugs, such as hydrocortisone, and even macromolecules, such as insulin, as demonstrated by the authors, thus serving as a simple physical solution to the barrier challenge in gastrointestinal drug delivery.Author: Carl M. Schoellhammer, Avi Schroeder, Avi Schroeder, Ruby Maa, Gregory Yves Lauwers, Albert Swiston,...
https://en.wikipedia.org/wiki/Therapeutic_ultrasound
Therapeutic ultrasound refers generally to any type of ultrasonic procedure that uses ultrasound for therapeutic benefit. Physiotherapeutic ultrasound was introduced into clinical practice in the 1950s, with lithotripsy introduced in the 1980s. Others are at various stages in transitioning from research to clinical use: HIFU, targeted ultrasound drug delivery, trans-dermal ultrasound drug ...
https://www.medscape.com/viewarticle/899089
Sep 25, 2019 · "This is the first-in-human and proof-of-principle study to show that drug delivery can be enhanced at the site where it is required by heating the tissue with focused ultrasound to activate the ...
https://www.fusfoundation.org/mechanisms-of-action/drug-delivery-vehicles
Stable cavitation induces acoustic streaming and increases cell membrane permeability 8, which also locally increases drug bioavailability. Clinically, combining focused ultrasound with drug delivery vehicles presents an attractive method for chemotherapy delivery.
https://www.sciencedaily.com/releases/2018/03/180320084420.htm
Mar 20, 2018 · Ultrasound mediated, targeted drug delivery is an emerging therapy approach with great potential and we are delighted to be in the forefront of this development."
https://www.medgadget.com/2018/09/focused-ultrasound-and-intranasal-drug-delivery-for-brain-cancer-therapy.html
Focused Ultrasound and Intranasal Drug Delivery for Brain Cancer Therapy. September 10th, 2018. Conn Hastings ENT, Neurology, Neurosurgery, Oncology.
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