Tumour Targeting Drug Delivery Systems

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(PDF) Tumor therapy: Targeted drug delivery systems

    https://www.researchgate.net/publication/307091675_Tumor_therapy_Targeted_drug_delivery_systems
    Recently, targeted drug delivery systems (TDDSs) have been extensively studied as a promising therapeutic for tumor therapy. In this review, we investigate the typical targeting mechanisms of ...

Mesoporous silica nanoparticle-based intelligent drug ...

    https://royalsocietypublishing.org/doi/10.1098/rsos.170986
    Mesoporous silica nanoparticle-based intelligent drug delivery system for bienzyme-responsive tumour targeting and controlled release Abstract In this system, MSNs were first modified by active targeting moiety hyaluronic acid (HA) for breast cancer cell targeting and hyaluronidases (Hyal)-induced intracellular drug release.

pH-responsive Virus-like Nanoparticles with Enhanced ...

    https://www.nature.com/articles/srep37891
    Nov 24, 2016 · pH-responsive Virus-like Nanoparticles with Enhanced Tumour-targeting Ligands for Cancer Drug Delivery Skip to main content Thank you for visiting nature.com.

An overview of active and passive targeting strategies to ...

    https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.13098
    Nuclear targeting. Beside the drug delivery to the TME or more precisely to the tumour cells, some treatments need an even more precise level which is the drug delivery at organelle level, for example, nucleus, lysosomes, mitochondria or endoplasmic reticulum.

Tumor target amplification: Implications for nano drug ...

    https://www.researchgate.net/publication/323221501_Tumor_target_amplification_Implications_for_nano_drug_delivery_systems
    Nano-drug delivery systems can provide much more effective and targeted delivery of anti-tumor drugs than the ... Tumour‐targeting bacteria‐based cancer therapies for increased specificity and ...

Tumor (Cancer) (Neoplastic) Targeted Drug Delivery ...

    http://www.authorstream.com/Presentation/siri1515-1478182-tumor-cancer-neoplastic-targeted-drug-delivery/
    Tumor targets (over expressed on tumor cells) Tumor-associated antigens Growth factor receptors Incorporation of biorecognizable moiety into drug delivery systems will lead to actively-targeted drug delivery systems 12 Byrne JD et al. Adv Drug Delivery Rev. 2008;60:1615-1626. ACTIVE TARGETING Active targeting

DRUG TARGETING: BASIC CONCEPTS AND DRUG CARRIER SYSTEMS …

    https://www.pharmatutor.org/articles/drug-targeting-basic-concepts-drug-carrier-systems-review
    • Insufficient localization of targeted systems into tumour cells. • Diffusion and redistribution of released drugs. Ideal characteristics of targeted drug delivery system: • Targeted drug delivery system should be- biochemically inert (non-toxic), non-immunogenic. • …

Targeting brain tumours with improved drug delivery systems

    https://ecancer.org/en/video/4581-targeting-brain-tumours-with-improved-drug-delivery-systems
    Dr Brem talks to ecancertv at Children with Cancer UK’s workshop on Drug Delivery in Paediatric Brain Tumours in London, UK.. He discusses how improved drug delivery systems have started to improve the therapeutic options for patients with brain tumours.

Targeted drug delivery - Wikipedia

    https://en.wikipedia.org/wiki/Drug_targeting
    Targeted drug delivery can be used to treat many diseases, such as the cardiovascular diseases and diabetes. However, the most important application of targeted drug delivery is to treat cancerous tumors. In doing so, the passive method of targeting tumors takes advantage of the enhanced permeability and retention (EPR) effect. This is a ...

Drug delivery and targeting. - 550058

    https://www.ibiology.org/speakers-pdf/Langer392_Nat_Sup_98.pdf
    such systems become practical. Yet in a Short time, new drug-delivery systems have had an impact on nearly every branch Of medicine including cardiology, ophthalmology, endocrinology, oncology, pul- monology, immunology and pain management. Annual sales in the United States Of advanced drug-delivery systems exceed $10 billion

Journal of Drug Targeting: Vol 28, No 4

    https://www.tandfonline.com/toc/idrt20/current
    A MEDLINE-indexed journal dedicated to all aspects of drug delivery and targeting for molecular and macromolecular drugs. Special areas of interest include the design and characterization of carrier systems for both vitro and in vivo applications. It offers accelerated publication.

Stimuli-responsive nanoscale drug delivery systems for ...

    https://www.tandfonline.com/doi/abs/10.1080/1061186X.2018.1519029
    AbstractCurrently, with the rapid development of nanotechnology, novel drug delivery systems (DDSs) have made rapid progress, in which nanocarriers play an important role in the tumour treatment. I...

Drug Delivery Systems - nibib.nih.gov

    https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
    Current research on drug delivery systems can be described in four broad categories: routes of delivery, delivery vehicles, cargo, and targeting strategies. Routes of Delivery. Medications can be taken in a variety of ways—by swallowing, by inhalation, …

pH-sensitive drug-delivery systems for tumor targeting ...

    https://www.future-science.com/doi/10.4155/tde.13.120
    Drug-delivery system responses to stimuli have been well investigated recently. As pH decrease is observed in most solid tumors, drug-delivery systems responsive to the slightly acidic extracellular pH environment of solid tumors have been developed as a general strategy for tumor targeting.

Nano based drug delivery systems: recent developments and ...

    https://jnanobiotechnology.biomedcentral.com/articles/10.1186/s12951-018-0392-8
    Therefore, using new drug delivery systems for targeting drugs to specific body parts could be an option that might solve these critical issues [9, 10]. Hence, nanotechnology plays a significant role in advanced medicine/drug formulations, targeting arena and their controlled drug release and delivery with immense success.

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