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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272876/
Aug 10, 2011 · For cancer therapies, the ideal targeted drug delivery system is the one that delivers the drug only to the target tumor. The reality, however, is far away from that ideal scenario. The amount of drug delivered to tumor targets is much less than 5% at most.Author: You Han Bae, Kinam Park
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7047275/
Feb 26, 2020 · Nanoparticles have been widely used in tumor targeted drug delivery, while the antitumor effects are not always satisfactory due to the limited penetration and retention. As we all know, there is a paradox that nanoparticles with large sizes tend to distribute around tumor blood vessels rather than penetrate into tumor parenchyma, while smaller sizes can penetrate deeply but with poor tumor retention.
https://onlinelibrary.wiley.com/doi/full/10.1002/adma.201904997
Tumor‐Targeted Drug and CpG Delivery System for Phototherapy and Docetaxel‐Enhanced Immunotherapy with Polarization toward M1‐Type Macrophages on Triple Negative Breast Cancers Lv Chen Breast Cancer Center, Shanghai East Hospital, Tongji University, Shanghai, 200120 P. R. ChinaAuthor: Lv Chen, Lulu Zhou, Chunhui Wang, Yi Han, Yonglin Lu, Jie Liu, Xiaochun Hu, Tianming Yao, Yun Lin, S...
https://www.researchgate.net/publication/307091675_Tumor_therapy_Targeted_drug_delivery_systems
Recently, targeted drug delivery systems (TDDSs) have been extensively studied as a promising therapeutic for tumor therapy.
https://www.sciencedirect.com/science/article/pii/S0928493119312032
Cell membrane-coated nanocarriers actively targeting tumor sites are known to circumvent the limitations of conventional treatments and nanosized drug delivery systems. Cell membrane-coated nanocarriers can evade the immune system and can target tumors, thereby exhibiting a prolonged circulation time, enhancing tumor accumulation, increasing cancer therapeutic efficacy, and facilitating tumor imaging …Author: Zehui He, Yongtai Zhang, Nianping Feng
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Tumor-targeted drug delivery systems based on supramolecular interactions between iron oxide–carbon nanotubes and polyamidoamine–polyethylene glycol–polyamidoamine (PAMAM–PEG–PAMAM ...Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
http://www.authorstream.com/Presentation/legendpoluprasad-2207763-tumor-targeting-ppt/
Jul 13, 2014 · Targeted drug delivery Targeted drug delivery system is achieved with the advantage of morphology and physiological differences between the normal cells and tumor cells. 11 Principles of drug targeting to tumors Passive targeting, Active targeting to cancer cells Active targeting to endothelial cells Triggered drug delivery...
https://www.slideshare.net/anushanagraj/targeted-drug-delivery-system
Sep 11, 2014 · CARRIER OR MARKERS : • Targeted drug delivery can be achieved by using carrier system. • Carrier is one of the special molecule or system essentially required for effective transportation of loaded drug up to the pre selected sites.
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
Drug delivery systems are engineered technologies for the targeted delivery and/or controlled release of therapeutic agents. Drugs have long been used to improve health and extend lives. The practice of drug delivery has changed dramatically in the past few decades and even greater changes are anticipated in the near future.
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