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http://www.authorstream.com/Presentation/legendpoluprasad-2207763-tumor-targeting-ppt/
Jul 13, 2014 · Triggered drug delivery The tumor microenvironment differs from that normal cells microenvironment Advantage of the difference in pH, temperature is used to release the drug in the tumor microenvironment It employs drug-carrier constructs that release drug only when exposed to specific microenvironments such as change in pH and temperature .
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3998643/
Patients can be treated with the drug prior to a planned tumor resection and the resected tissue is sampled for drug concentration and markers of drug activity. This approach is desirable for large agents or agents expected to be membrane bound, but it requires that the patient has surgery, provides drug concentration at only one time point, and allows for possible contamination of the samples by peripheral blood.Author: Jaishri Blakeley
https://science.sciencemag.org/content/279/5349/377.full
Jan 16, 1998 · When coupled to the anticancer drug doxorubicin, two of these peptides—one containing an αv integrin–binding Arg-Gly-Asp motif and the other an Asn-Gly-Arg motif—enhanced the efficacy of the drug against human breast cancer xenografts in nude mice and also reduced its toxicity.Author: Wadih Arap, Renata Pasqualini, Erkki Ruoslahti
https://www.slideshare.net/tasnimfarihanoshin/targeted-drug-delivery-to-tumor
Mar 20, 2015 · Targeted drug delivery to tumor. 1. Tasnim fariha noshin Nazmul huda Farzana naznin Ariful islam Noakhali Science & Technology University, Pharmacy Dpt. 2. Tumors are a classic sign of inflammation. It is a fluid-filled lesion that may or may not be formed by an abnormal growth of neoplastic cells that appears enlarged in size.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272876/
Aug 10, 2011 · The ultimate goal of drug delivery research is to help patients by developing clinically useful formulations. During the last several decades controlled drug delivery technology has advanced significantly, leading to the development of various clinical formulations improving patient compliance and convenience . Current technologies allow delivery of drugs at desired release kinetics for …Author: You Han Bae, Kinam Park
https://www.researchgate.net/publication/307091675_Tumor_therapy_Targeted_drug_delivery_systems
Tumor therapy: targeted drug delivery systems Liangliang Dai, Junjie Liu, Zhong Luo, Menghuan Li and Kaiyon g Cai* Recentl y, targe ted drug deli very sys tems (TDDS s) have bee n extensi vely ...
http://www.authorstream.com/Presentation/siri1515-1478182-tumor-cancer-neoplastic-targeted-drug-delivery/
Tumor targets (over expressed on tumor cells) Tumor-associated antigens Growth factor receptors Incorporation of biorecognizable moiety into drug delivery systems will lead to actively-targeted drug delivery systems 12 Byrne JD et al. Adv Drug Delivery Rev. 2008;60:1615-1626.
https://www.powershow.com/viewht/7aa0f-ZDc1Z/Nanotechnology_Based_Drug_Delivery_powerpoint_ppt_presentation
Dendrimer-based nanotechnology carriers for targeted drug delivery The right drug, to the right place, at the right time - Diffuse out of vasculature ( 20 nm) Recognize target cells and bind with high ... (ester-linked cytotoxic agent) 8. The Value of AvidimersTM for Drug Delivery ... PowerPoint PPT presentation free to view
https://www.slideshare.net/anushanagraj/targeted-drug-delivery-system
Sep 11, 2014 · • Targeted drug delivery seeks to concentrate the medication in the tissues of interest while reducing the relative concentration of the medication in the remaining tissues. • This improves efficacy and reduce side effects. 4. THE DRUG MAY BE DELIVERED : • …
https://www.nature.com/articles/s41392-017-0004-3
Mar 16, 2018 · Tumor-targeted drug delivery systems based on supramolecular interactions between iron oxide–carbon nanotubes and polyamidoamine–polyethylene glycol–polyamidoamine (PAMAM–PEG–PAMAM ...Author: Sudipta Senapati, Arun Kumar Mahanta, Sunil Kumar, Pralay Maiti
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