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https://www.sciencedirect.com/science/article/pii/S0022354916307626
The current pharmaceuticals in the United States that are formulated as liposome drug delivery systems are mainly antifungal and anticancer therapies; many more products, including those used as analgesics, gene therapies, and vaccines, are being developed.Author: Tianshun Lian, Rodney J.Y. Ho
https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/jps.1023
MINIREVIEW Trends and Developments in Liposome Drug Delivery Systems TIANSHUN LIAN, RODNEY J. Y. HO Department of Pharmaceutics, University of Washington, Box 357610 H272, Health Sciences Building, Seattle,Author: Tianshun Lian, Rodney J.Y. Ho
https://www.ncbi.nlm.nih.gov/pubmed/11357170
Since the discovery of liposomes or lipid vesicles derived from self-forming enclosed lipid bilayers upon hydration, liposome drug delivery systems have played a significant role in formulation of potent drugs to improve therapeutics.Author: Tianshun Lian, Rodney J.Y. Ho
https://www.sciencedirect.com/science/article/abs/pii/S0022354916307626
Trends and Developments in Liposome Drug Delivery Systems. Author links open overlay panel ... Additional refinements of biomembrane sensors and liposome delivery systems that are effective in the presence of other membrane‐bound proteins in vivo may permit selective delivery of therapeutic compounds to selected intracellular target ...Author: Tianshun Lian, Rodney J.Y. Ho
https://www.onlinelibrary.wiley.com/doi/abs/10.1002/jps.1023
Trends and developments in liposome drug delivery systems Tianshun Lian Department of Pharmaceutics, University of Washington, Box 357610 H272, Health Sciences Building, Seattle, Washington 98195Author: Tianshun Lian, Rodney J.Y. Ho
https://www.academia.edu/1015614/Trends_and_developments_in_liposome_drug_delivery_systems
MINIREVIEW Trends and Developments in Liposome Drug Delivery Systems TIANSHUN LIAN, RODNEY J. Y. HO Department of Pharmaceutics, University of Washington, Box 357610 H272, Health Sciences Building, Seattle, Washington 98195 Received 16 August 2000; revised 16 October 2000; accepted 19 October 2000 ABSTRACT: Since the discovery of liposomes or lipid vesicles derived …
https://www.researchgate.net/publication/11981150_Trends_and_developments_in_liposome_drug_delivery_systems
The insight gained from clinical use of liposome drug delivery systems can now be integrated to design liposomes targeted to tissues and cells with or without expression of target recognition ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4074410/
Since our last review on liposome drug delivery systems, 10 research continues to fuel development of liposomes and lipid nanoparticles that improve the pharmacokinetics and therapeutic index of drugs by extending their margin of safety and efficacy. This manuscript discusses the emerging research and clinical developments in liposome and lipid nanoparticle delivery of therapeutics.Author: John C. Kraft, Jennifer P. Freeling, Ziyao. Wang, Rodney J.Y. Ho
https://www.naturalmedicinejournal.com/blog/secret-effective-liposomal-delivery
In one study, cellular intake increased 9-fold as the liposome size was decreased from 236 nm to 97 nm, and cellular intake was increased 34-fold at 64 nm. 3 In addition, the therapeutic capabilities of a liposomal delivery system are also related to how fast the body clears the liposomes from the blood.
https://liposomes.weebly.com/history1.html
1965: Alec Bangham described the first closed bilayer phospholipid systems, first called "bangosomes," now called liposomes. 1971: Gregory Gregoriadis proposed the use of liposomes for drug delivery. Problems with the first generation liposomes: 1.) Entrapped molecules frequently leaked out of the liposomal membrane. - In order to “tighten” the membrane and thus prevent leakage ...
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