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https://www.nature.com/articles/nature05901
Jun 17, 2007 · A major impediment in the treatment of neurological diseases is the presence of the blood–brain barrier, which precludes the entry of therapeutic molecules from blood to brain. Here we show that a short peptide derived from rabies virus glycoprotein (RVG) enables the transvascular delivery of small interfering RNA (siRNA) to the brain.Author: Priti Kumar, Haoquan Wu, Jodi L. McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L. Davidson, Sang K...
https://ohsu.pure.elsevier.com/en/publications/transvascular-delivery-of-small-interfering-rna-to-the-central-ne-2
Jul 07, 2007 · Here we show that a short peptide derived from rabies virus glycoprotein (RVG) enables the transvascular delivery of small interfering RNA (siRNA) to the brain. This 29-amino-acid peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.Author: Priti Kumar, Haoquan Wu, Jodi L. McBride, Kyeong-Eun Jung, Moon Hee Kim, Beverly L. Davidson, Sang K...
https://www.semanticscholar.org/paper/Transvascular-delivery-of-small-interfering-RNA-to-Kumar-Wu/47ef327207c9d8bff4cab233a516beefa9ad6397
Here we show that a short peptide derived from rabies virus glycoprotein (RVG) enables the transvascular delivery of small interfering RNA (siRNA) to the brain. This 29-amino-acid peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.
https://www.researchgate.net/publication/6263796_Transvascular_delivery_of_small_interfering_RNA_to_the_central_nervous_system
(RVG) enables the transvas cular delivery of small interfering RNA (siRNA) to the brain. This 29-amino-acid peptide specifically bind s to the acetylcholine receptor expressed by neuronal cells.
https://www.academia.edu/18044726/Transvascular_delivery_of_small_interfering_RNA_to_the_central_nervous_system
Transvascular delivery of small interfering RNA to the central nervous system
https://www.the-scientist.com/papers-to-watch/transvascular-sirna-delivery-46181
Transvascular siRNA Delivery The tight network of endothelial cells of brain capillaries have, until now, kept therapeutic molecules, such as small interfering RNAs (siRNAs), from crossing from the blood into the brain. Such molecules could potentially silence targeted genes expressed in neurologic disorders. N.
https://www.researchgate.net/profile/Jodi_Mcbride2/publication/6263796_Transvascular_delivery_of_small_interfering_RNA_to_the_central_nervous_system/links/553d86600cf2c415bb0f72d4/Transvascular-delivery-of-small-interfering-RNA-to-the-central-nervous-system.pdf
(RVG) enables the transvascular delivery of small interfering RNA (siRNA) to the brain. This 29-amino-acid peptide specifically binds to the acetylcholine receptor expressed by neuronal cells.
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