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the development of transungual delivery. Penetration of topical antifungal through the nail plate requires a vehicle that is specifically formulated for transungual delivery. Recent focus is emphasizing on development of a promising antifungal treatment in form of nail lacquer owing to its beneficial advantages.Author: Vivek B Rajendra, Anjana Baro, Abha Kumari, Dinesh L Dhamecha, Swaroop R Lahoti, Santosh D Shelke
https://www.ncbi.nlm.nih.gov/pubmed/22149347
Minimally invasive electrically mediated techniques such as iontophoresis have gained success in facilitating the transungual delivery of actives. In addition drug transport across the nail plate has been improved by filing the dorsal surface of the nail plate prior to application of topical formulation.Author: H. N. Shivakumar, Abhishek Juluri, B. G. Desai, S. Narasimha Murthy
https://www.sciencedirect.com/science/article/pii/S037851730900711X
Despite containing the lowest active drug concentration, the marketed gel produced the greatest transungual ciclopirox delivery. We hypothesize that this particular gel formulation may effectively improve nail hydration, thus enhancing nail permeability.Author: Rania Elkeeb, Ali AliKhan, Laila Elkeeb, Xiaoying Hui, Howard I. Maibach
https://www.sciencedirect.com/science/article/pii/S1773224714500494
Transungual drug delivery: an update. Topical therapy continues to be the treatment of choice for the patients and clinicians in treating certain infections of the nails.Author: H.N. Shivakumar, M.A. Repka, S. Narasimha Murthy
https://www.researchgate.net/publication/285954824_Transungual_drug_delivery_An_overview
The nail lacquer is a new drug delivery system in treatment of nail infections. The major hurdle The major hurdle associated with devel oping n ail l acquers treatmen t fo r n ail di sorders is to ...
http://www.authorstream.com/Presentation/devsthali-1894082-transungual-drug-delivery-system/
Jul 31, 2013 · Transungual drug delivery system is targeted drug delivery system of the nail to treat diseases of nail itself. In the human nail plate is the most visible part of the nail apparatus which is responsible for penetration of drug across it.
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