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https://www.sciencedirect.com/science/article/pii/S0169409X04002686
Transmembrane delivery of protein and peptide drugs by TAT-mediated transduction in the treatment of cancer. Author links open overlay panel Jehangir S. Wadia Steven F. Dowdy. Show more. ... Delivery of fusion proteins by conjugation to the TAT transduction domain.Author: Jehangir S. Wadia, Steven F. Dowdy
https://www.sciencedirect.com/science/article/pii/S0168365920300936
In this study, a safe, efficient, and easy-to-prepare MS for transmembrane delivery has been successfully developed. The MT was fabricated by LbL self-assembly, which could use many materials with positive or negative charges (CHI and ALG was used in this paper).Author: Zhongping Liang, Hang Yu, Jianfeng Lai, Lu Wen, Gang Chen
https://www.ncbi.nlm.nih.gov/pubmed/26964879
Apr 07, 2016 · Herein, transmembrane delivery of a series of small molecule anticancer drugs was achieved by the construction of artificial transmembrane nanochannels formed by self-assembly of cyclic peptide (cyclo[Gln-(d-Leu-Trp)4-d-Leu], CP) nanotubes (CPNTs) in the lipid bilayers.Author: Jian Chen, Bei Zhang, Fei Xia, Yunchang Xie, Sifan Jiang, Rui Su, Yi Lu, Wei Wu
https://www.ncbi.nlm.nih.gov/pubmed/20821386
In conclusion, TD/GH counteracted brain defects in aged mice in vivo and cell apoptosis induced by Aβ in vitro might explain several underlying mechanisms by which GH could ameliorate learning and memory deficits in aged mice. Mixed TD/GH transmembrane delivery might be a …Author: Ting Zhang, Hengyan Qu, Xuling Li, Baoquan Zhao, Jianping Zhou, Qian Li, Manji Sun
https://onlinelibrary.wiley.com/doi/full/10.1002/wnan.1606
Transmembrane delivery of siRNA represents a new avenue for efficient delivery by bypassing the endosomal pathway. This rationale is bolstered by the high efficiency of viral entry by membrane fusion, but rarely pursued by artificial siRNA delivery systems.Author: Yan Zheng, Wanyi Tai
https://www.pnas.org/content/95/9/5003
Apr 28, 1998 · Results herein suggest that a family of integral membrane proteins in prokaryotes, protozoans, and plants act as transmembrane heme delivery systems for the biogenesis of c -type cytochromes. The complete topology of a representative from each of the three subfamilies was experimentally determined.Author: Barry S. Goldman, David L. Beck, Elizabeth M. Monika, Robert G. Kranz
https://pubs.acs.org/doi/10.1021/acsami.9b04967
Metal ion synergistically enhanced chemotherapy is a promising strategy for cancer treatment. However, targeting delivery of ions toward cancer cells remains challenging for decades. Herein, we developed a novel folic acid-nanogel (termed as FA-nanogel) with alkane chains as diffusion barriers for targeted transmembrane delivery of calcium ions into cancer cells. With the aid of hydrophobic ...Author: Shan-Wen Hu, Shan-Wen Hu, Jin Wang, Ting-Ting Zhang, Xiang-Ling Li, Hong-Yuan Chen, Jing-Juan Xu
https://pubs.acs.org/doi/abs/10.1021/acs.biomac.6b01678
Polycations are popular agents for nonviral delivery of DNA to mammalian cells. Adding hydrophobic, biodegradable, or cell-penetrating functions could help to improve their performance, which at present is below that of viral agents. A crucial first step in gene delivery is the complexation of the DNA. The characteristics of these “polyplexes” presumably influence or even determine the ...Author: Alexander Raup, Hui Wang, Christopher V. Synatschke, Valérie Jérôme, Seema Agarwal, Dmitry V. Pergus...
https://en.wikipedia.org/wiki/Transmembrane
A transmembrane protein (TP) is a type of integral membrane protein that spans the entirety of the cell membrane.Many transmembrane proteins function as gateways to permit the transport of specific substances across the membrane. They frequently undergo significant conformational changes to move a substance through the membrane. They are usually highly hydrophobic and aggregate and precipitate ...
https://quizlet.com/281723905/biology-1407-chapter-36-flash-cards/
In the transmembrane route for transport within plant tissue, _____. Water and solutes move out of one cell, across the cell wall, and into the neighboring cell Ignoring all other factors, what kind of day would result in the fastest delivery of water and minerals to the leaves of an oak tree?
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