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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Transdermal drug delivery has made an important contribution to medical practice, but has yet to fully achieve its potential as an alternative to oral delivery and hypodermic injections. First-generation transdermal delivery systems have continued their steady increase in clinical use for delivery of small, lipophilic, low-dose drugs.Author: Mark R Prausnitz, Robert Langer
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695828/
Oct 22, 2015 · 2. Transdermal Drug Delivery (TDD) TDD is a painless method of delivering drugs systemically by applying a drug formulation onto intact and healthy skin [2,5].The drug initially penetrates through the stratum corneum and then passes through the deeper epidermis and dermis without drug accumulation in the dermal layer.Author: Ahlam Zaid Alkilani, Maelíosa T.C. McCrudden, Ryan F. Donnelly
https://academic.oup.com/bjaed/article/7/5/171/535087
Oct 01, 2007 · Transdermal delivery systems. There are two designs of transdermal patch currently available: the reservoir, or membrane-controlled system, and the matrix system. A reservoir patch holds the drug in a gel or solution and delivery is determined by a rate-controlling membrane between the drug reservoir and the skin (Fig. 3).Author: Lyn Margetts, Richard Sawyer
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
Transdermal Drug Delivery System. Transdermal therapeutic systems (TTS) were introduced as devices displaying the ability to release an active agent to the skin in a controlled manner, well below the maximum the tissue can accept. From: Strategies to Modify the …
https://www.researchgate.net/publication/261759007_TRANSDERMAL_DRUG_DELIVERY_SYSTEM_A_REVIEW
Transdermal drug delivery has made an important contribution to medical practice, but it has yet to fully achieve its potential as an alternative to the oral delivery and hypodermic injections.
https://www.sciencedirect.com/science/article/pii/S0169409X17301801
Although the betterment of transdermal delivery so far has focused on maximizing the delivery efficiency, transdermal drug delivery is yet to see another breakthrough by adopting a paradigm shift towards personalized therapy , , .Furthermore, transdermal delivery is set to adopt an advanced paradigm of device-assisted personalized therapy where the precise control of the amount and duration of ...Author: Hyunjae Lee, Changyeong Song, Seungmin Baik, Dokyoon Kim, Taeghwan Hyeon, Dae-Hyeong Kim
https://medical-dictionary.thefreedictionary.com/transdermal+drug+delivery
Transdermal drug delivery has some benefits: skipping first pass metabolism in liver, steady infusion of a drug over an extended period of time, better compliance of the patient due to ease of usage and reduced frequency of use, a choice for drugs with low therapeutic index and short half life, and so easy elimination of drug when toxicity occurs during the application [3,5,6].
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