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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2700785/
Today, there are 19 transdermal delivery systems for such drugs as estradiol, fentanyl, lidocaine and testosterone; combination patches containing more than one drug for contraception and hormone replacement; and iontophoretic and ultrasonic delivery systems for analgesia (Table 1, Fig. 1). Between 1979 and 2002, a new patch was approved on average every 2.2 years.Author: Mark R Prausnitz, Robert Langer
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/transdermal-delivery
Transdermal drug delivery systems also termed as “patches” are self-contained discrete dosage forms designed to deliver a therapeutically effective amount of drug through intact skin (Wokovich et al., 2006). Most commercially available transdermal drug delivery systems are of three different types, namely reservoir systems, matrix systems with rate-controlling membrane, and matrix systems without rate …
https://www.sciencedirect.com/topics/nursing-and-health-professions/transdermal-drug-delivery-system
Transdermal drug delivery systems (TDDS) have generated extensive interest as a preferred alternative to oral drug delivery and hypodermic injections, ever since the first scopolamine transdermal patch for motion sickness was approved by the US Food and Drug Administration in 1979 [1].
https://www.fdanews.com/ext/resources/files/2019/11-20-19-TDSdraftguidance.pdf?1574288455
Transdermal delivery systems are designed to deliver an active ingredient (drug substance) 36 across the skin and into systemic circulation, while topical delivery systems are designed to 37 deliver the active ingredient to local tissue.
https://biomeddermatol.biomedcentral.com/articles/10.1186/s41702-020-0058-7
Transdermal delivery systems have been intensively studied over the past 2 decades, with the focus on overcoming the skin barrier for more effective application of pharmaceutical and cosmetic products.
http://ijpsr.com/bft-article/transdermal-drug-delivery-system-a-review/?view=fulltext
The main objective of transdermal drug delivery system is to deliver drugs into systemic circulation into the skin through skin at predetermined rate with minimal inter and intra patient variation. 3 Currently transdermal delivery is one of the most promising methods for drug application.
https://www.researchgate.net/publication/270015915_Transdermal_drug_delivery_system_An_overview
Transdermal drug delivery system (TDDS) is one of the systems lying under the category of controlled drug delivery, in which the aim is to deliver the drug through the skin in a predetermined and controlled rate. It has various advantages, like prolonged therapeutic effect, reduced side-effects,...
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