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https://pubchem.ncbi.nlm.nih.gov/patent/US8246979
An improved transdermal delivery system (TDS) comprises a self-adhesive matrix comprising a solid or semi-solid semi-permeable polymer which contains rotigotine in its free base form as a multitude of microreservoirs within the matrix.
https://patents.google.com/patent/US8246979B2/en
The self-adhesive matrix is highly permeable to the free base of rotigotine and is impermeable to the protonated form of rotigotine. An improved transdermal delivery system (TDS) comprises a self-adhesive matrix comprising a solid or semi-solid semi-permeable polymer which contains rotigotine in its free base form as a multitude of microreservoirs within the matrix.Author: Dietrich Wilhelm Schacht, Mike Hannay, Hans-Michael Wolff
https://patents.google.com/patent/US8617591B2/en
An improved Transdermal Delivery System (TDS) comprising a backing layer inert to the components of the matrix, a self-adhesive matrix containing rotigotine and a protective foil or sheet to be removed prior to use, characterized in that the self-adhesive matrix consists of a solid or semi-solid semi-permeable polymer (1) wherein rotigotine in its free base form has been incorporated, (2) which is saturated with …Author: Dietrich Wilhelm Schacht, Mike Hannay, Hans-Michael Wolff
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2671947/
Rotigotine transdermal system, a new non-ergolinic dopamine agonist, was developed to provide a drug that can be applied once daily. To date, it is approved for the treatment of early Parkinson’s disease as monotherapy and has been shown to be effective in the treatment of advanced-stage Parkinson’s disease and RLS in several clinical trials.Author: Sabine Bunten, Svenja Happe
https://www.rxlist.com/neupro-drug.htm
Jan 04, 2019 · Neupro is a transdermal system that provides continuous delivery of rotigotine, a non-ergoline dopamine agonist, for 24 hours following application to intact skin. Neupro is available in six strengths as shown in Table 4.
https://www.drugs.com/mtm/rotigotine-transdermal.html
Rotigotine transdermal (skin patch) is used to treat symptoms of Parkinson's disease, such as stiffness, tremors, muscle spasms, and poor muscle control. Rotigotine is also used to treat restless legs syndrome (RLS). Rotigotine may also be used for purposes not listed in this medication guide.7.7/10
https://www.webmd.com/drugs/2/drug-148554/neupro-transdermal/details
Neupro Patch, Transdermal 24 Hours. Rotigotine is used alone or with other medications to treat Parkinson's disease. It can improve your ability to move and decrease shakiness (tremor), stiffness, slowed movement, and unsteadiness. Rotigotine is also used to treat restless legs syndrome (RLS).
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