We have collected information about Transdermal Delivery Of Melatonin for you. Follow the links to find out details on Transdermal Delivery Of Melatonin.
https://pdfs.semanticscholar.org/79de/7ba337bad475793362de78be5a44a6d48646.pdf
The transdermal drug delivery is a good alternative for melatonin delivery because of its variable oral absorption, short half-life, highly first pass metabolism, and a favorable partition coefficient.
https://www.researchgate.net/publication/26674503_Use_of_Transdermal_Melatonin_Delivery_to_Improve_Sleep_Maintenance_During_Daytime
that transdermal delivery of melatonin during the daytime can elevate plasma melatonin and reduce waking after sleep onset by promoting sleep in the latter part of an 8-hour sleep opportunity.
https://www.researchgate.net/publication/11095382_Effect_of_vehicles_on_the_transdermal_delivery_of_melatonin_across_porcine_skin_in_vitro
Melatonin is a good candidate for transdermal drug delivery considering its variable oral absorption, a short biological half-life and extensive first pass metabolism.
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