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https://www.sciencedirect.com/science/article/pii/S0025619611643188
Transcutaneous drug delivery has many theoretic and practical advantages and disadvantages, and such issues are often a concern for both clinicians and patients. This review of this relatively novel method of drug delivery serves as a foundation to address these concerns and provides practical knowledge for clinicians to optimize patient care.Author: Jeffrey J. Berti, James J. Lipsky
https://medical-dictionary.thefreedictionary.com/transcutaneous+drug+delivery
transcutaneous drug delivery: Transdermal therapy Therapeutics Use of topical prolonged-release forms of drugs; transcutaneous penetration of a drug requires that it traverse the intercellular lipid layer surrounding the cells of the stratum corneum–rather than through the cells themselves, but also the aqueous environment of the basal cells ...
https://www.ncbi.nlm.nih.gov/pubmed/15804178
The present investigation aimed at evaluating the role of fatty acid synthesis inhibition in enhancing transcutaneous delivery of levodopa (LD). Rat epidermis was treated with ethanol and various doses of cerulenin (an inhibitor of fatty acid synthase enzyme system) for reducing the normal level of fatty acids.Author: Kumar Babita, Ashok K. Tiwary
https://www.sciencedirect.com/science/article/pii/S0168365911011527
Administration of live virus-coated microneedle arrays successfully resulted in virus delivery, transcutaneous infection and induced an antibody or CD8 + T cell response in mice that was comparable to that obtained by needle-and-syringe intradermal immunization. To our knowledge, this is the first report of successful vaccination with ...Author: Anto Vrdoljak, Marie G. McGrath, John B. Carey, Simon J. Draper, Adrian V.S. Hill, Conor O'Mahony, A...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6920820/
Oct 30, 2019 · Transcutaneous delivery of antigen to the skin by S/O nanodispersions. (A) Skin sectioning fluorescence microscopy images of PE and PE-GM permeating the mouse-ear auricle skin in vivo and (B) the cumulative amount of PE and PE-GM in the skin following 6 h incubation in vitro with a PE or PE-GM PBS solution (PBS) and S/O nanodispersions (S/O ...Author: Qingliang Kong, Kouki Higasijima, Rie Wakabayashi, Yoshiro Tahara, Momoko Kitaoka, Hiroki Obayashi, ...
https://onlinelibrary.wiley.com/doi/full/10.1002/jgm.3089
The transcutaneous delivery of macromolecules or nanoparticles via laser‐generated micropores is a versatile and reproducible method for circumventing the SC barrier by thermally ablating the superficial SC with pulsed lasers. 71 By precisely controlling the laser fluence and pulse number, thermal damage of adjacent skin tissues would be ...Author: Xiaoyi Sun, Linghui Zeng, Yongzhuo Huang
https://medical-dictionary.thefreedictionary.com/transcutaneous
transcutaneous: [ trans″ku-ta´ne-us ] transdermal . transcutaneous electrical nerve stimulation (TENS) 1. use of a battery-powered device to relieve acute and chronic pain . Electrodes attached to the skin transmit electrical impulses, which produce a mild tingling, tapping, or massaging sensation. Reasons postulated for the effectiveness of ...
https://evidencebasedbirth.com/transcutaneous-electrical-nerve-stimulation-tens-for-pain-relief-during-labor/
May 22, 2018 · Hi, everyone! My name’s Rebecca Dekker, and I’m a nurse with my PhD and the Founder of EvidenceBasedBirth.com. In today’s video we’re going to talk about using TENS, or transcutaneous electrical nerve stimulation, for pain management during labor.
http://pubs.acs.org/doi/abs/10.1021/acsnano.6b04989
In light of this, we have developed a synergistic immunotherapy strategy that locally targets the immunoinhibitory receptor programmed cell death protein 1 (PD1) and immunosuppressive enzyme indoleamine 2,3-dioxygenase (IDO) for the treatment of melanoma through a microneedle-based transcutaneous delivery approach.Author: Yanqi Ye, Jinqiang Wang, Quanyin Hu, Gabrielle M. Hochu, Hongliang Xin, Chao Wang, Zhen Gu
https://www.woundsource.com/product-category/biophysical-agents/oxygen-therapy-transcutaneous
Transcutaneous oxygen therapy is a non-invasive method of providing oxygen to the wound bed to facilitate healing. Oxygen is of paramount importance to collagen formation, granulation, angiogenesis and epithelialization, and also plays an important role in controlling bacteria.
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