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https://drug-dev.com/topical-delivery-the-importance-of-the-right-formulation-in-topical-drug-development/
Topical formulations for pharmaceutical delivery are becoming increasingly popular. Topical delivery has a number of advantages: the ability to deliver drug substance more selectively to a specific site, avoiding fluctuations in drug levels, inter- and intra-patient variations, improved compliance, and an enhanced suitability for self-medication.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825625/
Topical drug delivery is a common strategy for local therapy and to reduce systemic adverse effects in the treatment of skin diseases. In order to reach therapeutic drug concentrations in the viable epidermal layer, effective drug permeation across the uppermost skin barrier, the …Author: Doungdaw Chantasart, Doungdaw Chantasart, Jinsong Hao, S. Kevin Li
https://www.fdanews.com/ext/resources/files/2019/11-20-19-TDSdraftguidance.pdf?1574288455
Transdermal delivery systems are designed to deliver an active ingredient (drug substance) 36 across the skin and into systemic circulation, while topical delivery systems are designed to 37 deliver the active ingredient to local tissue.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976443/
Jan 22, 2014 · Application of topical products to the skin can act locally or pass into the systemic circulation, or do both. Since its first approval by the US FDA scopolamine for motion sickness in December 1979 , many other were developed for transdermal and topical drug delivery (18-23).Author: Mir Sadat-Ali, Dalal A. Bubshait, Haifa A. Al-Turki, Dakheel A. Al-Dakheel, Wissam S. Al-Olayani
https://www.uea.ac.uk/business/licensing-opportunities/medical-and-life-sciences/topical-delivery
Topical Delivery Topical Delivery. A novel approach for the delivery of bioactive ingredients to the skin with cosmetic and pharmaceutical application potential. This novel, nanomaterial-based delivery method has superior sensation and appearance qualities to current products, offers high flexibility in terms of the active ingredients that can ...
https://www.nature.com/articles/nplants2016207
Jan 09, 2017 · This innovation translates nanotechnology developed for delivery of RNAi for human therapeutics to use in crop protection as an environmentally sustainable and easy to adopt topical spray.Author: Neena Mitter, Elizabeth A. Worrall, Karl E. Robinson, Peng Li, Ritesh G. Jain, Christelle Taochy, St...
https://appliedtissue.com/topical-delivery/
Topical Delivery of Pharmaceuticals to Skin and Wounds. Using the PWD provides safe and efficient topical delivery.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/transdermal-delivery
Transdermal Delivery. Transdermal delivery is the term that is confined to a situation in which the drug diffuses through different layers of the skin into systemic circulation to elicit the therapeutic response (Brown et al., 2006).
https://www.zrtlab.com/blog/archive/topical-delivery-of-sex-steroid-hormones-and-distribution-in-different-body-fluids/
Sep 12, 2019 · Delivery of the bioidentical hormones estradiol (E2), progesterone (Pg), and testosterone (T) through the skin as a cream or gel (topically) has become a mainstay of bioidentical hormone replacement therapy (BHRT) for women and men. A plethora of FDA-approved pharmaceuticals, compounded, and even over-the-counter topical BHRT products are ...
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