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https://web.nmsu.edu/~snsm/classes/chem435/Lab4/intro.html
Introduction. Thermodynamics of DNA Duplex Denaturing. Objective: The purpose of this lab is to evaluate thermodynamics of double helical DNA and determine: the dominant forces of interaction in DNA from its melting curve and ; the thermodynamic parameters of the single strand to helix transition
https://pubs.acs.org/doi/10.1021/jp004395k
The thermodynamic approach taken for this investigation is appropriate, but in order to improve conditions for better DNA delivery systems further investigations of other systems are needed. These systems will have to include variation of the copolymer length, changes in the hydrophilic−hydrophobic balance of the copolymer, as well as the sequence, length, and conformation of DNA.Author: Tatiana Bronich, Alexander Victorovich Kabanov, Luis A. Marky
https://pubs.acs.org/doi/10.1021/bi0203987
Oct 19, 2002 · However, membrane transport of DNA is an inefficient process, and the mechanism(s) by which this process occurs is not clear. Although viral vectors are effective in gene therapy, the immune response elicited by viral proteins poses a major problem. Therefore, several laboratories are involved in the development of nonviral DNA delivery vehicles.Author: Veena Vijayanathan, Thresia Thomas,§,‖ and, T. J. Thomas
https://blog-biosyn.com/2013/05/10/thermodynamics-of-dna-hybridization/
May 10, 2013 · Knowledge of DNA thermodynamics is crucial for the design of PCR probes or any other oligonucleotide based hybridization probe!. Since DNA hybridization does not strictly follow the Watson-Crick pairing rules DNA hybridization experiments often require optimization. A DNA oligonucleotide has the potential to pair with many sites on the genome including one or a few mismatches.
http://www.math.utah.edu/~palais/pcr/papers/SL2004.pdf
THERMODYNAMICS OF DNA MOTIFS 417 of biotechnology techniques that exploit the three-dimensional folding potential of DNA have also been demonstrated including DNA nanotechnology (75) and DNA computing (21). The DNA Folding Problem Similar to the protein and RNA folding problems, there is a corresponding “DNA
https://pubs.rsc.org/en/content/articlelanding/2018/sm/c7sm02456h#!
DNA-level physiochemical quantities, both thermodynamic and kinetic, are key to understanding this process and essential for the design of DNA-NP crystals. The melting transition properties are helpful to judge the thermostability and sensitivity of relative DNA probes or other applications.
https://chemistry.stackexchange.com/questions/66591/thermodynamics-of-dna-double-helix-formation
The entropy of a system decreases when 2 single stranded DNA molecules come together and form a double stranded molecule. For this to occur the total entropy of the universe must increase. Thus, heat is released when the double stranded molecule forms.
https://www.ncbi.nlm.nih.gov/pubmed/15139820
Accurate prediction of DNA secondary structure and hybridization using dynamic programming algorithms requires a database of thermodynamic parameters for several motifs including Watson-Crick base pairs, internal mismatches, terminal mismatches, terminal dangling ends, hairpins, bulges, internal loops, and multibranched loops.Author: John SantaLucia, Donald Hicks
https://www.thoughtco.com/laws-of-thermodynamics-373307
Jul 29, 2019 · This energy is needed to perform cell functions such as DNA replication, mitosis, meiosis, cell movement, endocytosis, exocytosis, and apoptosis. Second Law of Thermodynamics in Biological Systems As with other biological processes, the transfer of energy is not 100 percent efficient.Author: Regina Bailey
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