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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC538251/
Nov 16, 2004 · Besides the well known application of microbubbles as contrast agents for diagnostic ultrasound, microbubbles have also been demonstrated an effective technique for targeted delivery of drugs and genes [1-6]. Drugs can be incorporated into the microbubbles in a number of different ways, including binding of the drug to the microbubble shell and attachment of site-specific ligands.Author: Jeane M Tsutsui, Feng Xie, Richard Thomas Porter
https://www.ncbi.nlm.nih.gov/pubmed/17880272
Interest in microbubbles as vehicles for drug delivery has grown in recent years, due in part to characteristics that make them well suited for this role and in part to the need the for localized delivery of drugs in a number of applications. Microbubbles are inherently small, allowing transvascular passage, they can be functionalized for targeted adhesion, and can be acoustically driven, which …Author: Joseph L Bull
https://www.nibib.nih.gov/news-events/newsroom/targeted-drug-delivery-microbubbles
Sep 16, 2005 · The researchers’ goal is to have the pulse patterns used for guiding and then rupturing microbubbles integrated into conventional ultrasound machines, thereby linking diagnostic and therapeutic work. The team wants to develop a wider range of pulse sequences and drug-delivery vehicles to treat other diseases as well.
https://www.researchgate.net/publication/5963374_The_application_of_microbubbles_for_targeted_drug_delivery
Drug delivery with microbubbles and ultrasound is a promising technology and is gaining more and more attention in the field of the targeted drug delivery, especially in cancer drug delivery [6 ...
https://cardiovascularultrasound.biomedcentral.com/articles/10.1186/1476-7120-2-23
Nov 16, 2004 · Besides the well known application of microbubbles as contrast agents for diagnostic ultrasound, microbubbles have also been demonstrated an effective technique for targeted delivery of drugs and genes [1–6]. Drugs can be incorporated into the microbubbles in a number of different ways, including binding of the drug to the microbubble shell and attachment of site-specific ligands.
https://www.researchgate.net/publication/8179626_The_use_of_microbubbles_to_target_drug_delivery
Microbubbles are used to carry a drug or gene until a specific area of interest is reached, and then ultrasound is used to burst the microbubbles, causing site-specific delivery of the bioactive materials. Furthermore, the ability of albumin-coated microbubbles to adhere to vascular regions...
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